Yüklüyor......
RAD001 Enhances the Potency of BEZ235 to Inhibit mTOR Signaling and Tumor Growth
The mammalian target of rapamycin (mTOR) is regulated by oncogenic growth factor signals and plays a pivotal role in controlling cellular metabolism, growth and survival. Everolimus (RAD001) is an allosteric mTOR inhibitor that has shown marked efficacy in certain cancers but is unable to completely...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , , , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2012
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3498278/ https://ncbi.nlm.nih.gov/pubmed/23155392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048548 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|