Loading...

RAD001 Enhances the Potency of BEZ235 to Inhibit mTOR Signaling and Tumor Growth

The mammalian target of rapamycin (mTOR) is regulated by oncogenic growth factor signals and plays a pivotal role in controlling cellular metabolism, growth and survival. Everolimus (RAD001) is an allosteric mTOR inhibitor that has shown marked efficacy in certain cancers but is unable to completely...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Nyfeler, Beat, Chen, Yan, Li, Xiaoyan, Pinzon-Ortiz, Maria, Wang, Zuncai, Reddy, Anupama, Pradhan, Elina, Das, Rita, Lehár, Joseph, Schlegel, Robert, Finan, Peter M., Cao, Z. Alexander, Murphy, Leon O., Huang, Alan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498278/
https://ncbi.nlm.nih.gov/pubmed/23155392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048548
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!