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Effects of the mTOR inhibitor everolimus and the PI3K/mTOR inhibitor NVP-BEZ235 in murine acute lung injury models

The mammalian target of rapamycin (mTOR) is a key signaling kinase associated with a variety of cellular functions including the regulation of immunological and inflammatory responses. Classical mTOR inhibitors such as rapamycin or everolimus are commonly used in transplant as well as cancer patient...

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發表在:Transpl Immunol
Main Authors: Üstün, Sevdican, Lassnig, Caroline, Preitschopf, Andrea, Mikula, Mario, Müller, Mathias, Hengstschläger, Markus, Weichhart, Thomas
格式: Artigo
語言:Inglês
出版: 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6089344/
https://ncbi.nlm.nih.gov/pubmed/26073719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trim.2015.06.001
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