Utility of a PI3K/mTOR Inhibitor (NVP-BEZ235) for Thyroid Cancer Therapy

BACKGROUND: We assessed the utility of the dual PI3K/mTOR inhibitor NVP-BEZ235 (BEZ235) as single agent therapy and in combination with conventional chemotherapy for thyroid cancer. METHODOLOGY/PRINCIPAL FINDINGS: Eight cell lines from four types of thyroid cancer (papillary, follicular, anaplastic,...

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Главные авторы: Lin, Shu-Fu, Huang, Yu-Yao, Lin, Jen-Der, Chou, Ting-Chao, Hsueh, Chuen, Wong, Richard J.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471922/
https://ncbi.nlm.nih.gov/pubmed/23077520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046726
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