The landscape of kinase fusions in cancer

بواسطة Stransky, Nicolas, Cerami, Ethan, Schalm, Stefanie, Kim, Joseph L., Lengauer, Christoph
منشور في 2014

Targeting cancer with kinase inhibitors

بواسطة Gross, Stefan, Rahal, Rami, Stransky, Nicolas, Lengauer, Christoph, Hoeflich, Klaus P.
الحاوية / القاعدة J Clin Invest (2015)

Accuracy assessment of fusion transcript detection via read-mapping and de novo fusion transcript assembly-based methods

بواسطة Haas, Brian J., Dobin, Alexander, Li, Bo, Stransky, Nicolas, Pochet, Nathalie, Regev, Aviv
الحاوية / القاعدة Genome Biol (2019)

Inhibitor-Sensitive FGFR1 Amplification in Human Non-Small Cell Lung Cancer

بواسطة Dutt, Amit, Ramos, Alex H., Hammerman, Peter S., Mermel, Craig, Cho, Jeonghee, Sharifnia, Tanaz, Chande, Ajit, Tanaka, Kumiko Elisa, Stransky, Nicolas, Greulich, Heidi, Gray, Nathanael S., Meyerson, Matthew
منشور في 2011

A Novel Epigenetic Phenotype Associated With the Most Aggressive Pathway of Bladder Tumor Progression

بواسطة Vallot, Céline, Stransky, Nicolas, Bernard-Pierrot, Isabelle, Hérault, Aurélie, Zucman-Rossi, Jessica, Chapeaublanc, Elodie, Vordos, Dimitri, Laplanche, Agnès, Benhamou, Simone, Lebret, Thierry, Southgate, Jennifer, Allory, Yves, Radvanyi, François
منشور في 2011

A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein

بواسطة Pop, Marius S, Stransky, Nicolas, Garvie, Colin W, Theurillat, Jean-Philippe, Lewis, Timothy A, Zhong, Cheng, Culyba, Elizabeth K, Lin, Fallon, Daniels, Douglas S, Pagliarini, Raymond, Ronco, Lucienne, Koehler, Angela N, Garraway, Levi A
منشور في 2014

Nuclear factor I/B is an oncogene in small cell lung cancer

بواسطة Dooley, Alison L., Winslow, Monte M., Chiang, Derek Y., Banerji, Shantanu, Stransky, Nicolas, Dayton, Talya L., Snyder, Eric L., Senna, Stephanie, Whittaker, Charles A., Bronson, Roderick T., Crowley, Denise, Barretina, Jordi, Garraway, Levi, Meyerson, Matthew, Jacks, Tyler
منشور في 2011

Genomic analyses of gynaecologic carcinosarcomas reveal frequent mutations in chromatin remodelling genes

بواسطة Jones, Siân, Stransky, Nicolas, McCord, Christine L., Cerami, Ethan, Lagowski, James, Kelly, Devon, Angiuoli, Samuel V., Sausen, Mark, Kann, Lisa, Shukla, Manish, Makar, Rosemary, Wood, Laura D., Diaz, Luis A., Lengauer, Christoph, Velculescu, Victor E.
الحاوية / القاعدة Nat Commun (2014)

TYRO3 as a molecular target for growth inhibition and apoptosis induction in bladder cancer

بواسطة Dufour, Florent, Silina, Linda, Neyret-Kahn, Hélène, Moreno-Vega, Aura, Krucker, Clémentine, Karboul, Narjesse, Dorland-Galliot, Marion, Maillé, Pascale, Chapeaublanc, Elodie, Allory, Yves, Stransky, Nicolas, Haegel, Hélène, Menguy, Thierry, Duong, Vanessa, Radvanyi, François, Bernard-Pierrot, Isabelle
الحاوية / القاعدة Br J Cancer (2019)

ATARiS: Computational quantification of gene suppression phenotypes from multisample RNAi screens

بواسطة Shao, Diane D., Tsherniak, Aviad, Gopal, Shuba, Weir, Barbara A., Tamayo, Pablo, Stransky, Nicolas, Schumacher, Steven E., Zack, Travis I., Beroukhim, Rameen, Garraway, Levi A., Margolin, Adam A., Root, David E., Hahn, William C., Mesirov, Jill P.
منشور في 2013

Consistency of drug profiles and predictors in large-scale cancer cell line data

بواسطة Stransky, Nicolas, Ghandi, Mahmoud, Kryukov, Gregory V., Garraway, Levi A., Amzallag, Arnaud, Pruteanu-Malinici, Iulian, Haber, Daniel A., Ramaswamy, Sridhar, Benes, Cyril H., Lehár, Joseph, Liu, Manway, Sonkin, Dmitriy, Kauffmann, Audrey, Venkatesan, Kavitha, Edelman, Elena J., Riester, Markus, Barretina, Jordi, Caponigro, Giordano, Schlegel, Robert, Sellers, William, Stegmeier, Frank, Morrissey, Michael, Menden, Michael P., Iorio, Francesco, Stratton, Michael R., McDermott, Ultan, Saez-Rodriguez, Julio, Garnett, Mathew J.
الحاوية / القاعدة Nature (2015)

Genomic Correlate of Exceptional Erlotinib Response in Head and Neck Squamous Cell Carcinoma

بواسطة Van Allen, Eliezer M., Lui, Vivian W. Y., Egloff, Ann Marie, Goetz, Eva M., Li, Hua, Johnson, Jonas T., Duvvuri, Umamaheswar, Bauman, Julie E., Stransky, Nicolas, Zeng, Yan, Gilbert, Breean R., Pendleton, Kelsey P., Wang, Lin, Chiosea, Simion, Sougnez, Carrie, Wagle, Nikhil, Zhang, Fan, Du, Yu, Close, David, Johnston, Paul A., McKenna, Aaron, Carter, Scott L., Golub, Todd R., Getz, Gad, Mills, Gordon B., Garraway, Levi A., Grandis, Jennifer R.
الحاوية / القاعدة JAMA Oncol (2015)

Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer

بواسطة Cheung, Hiu Wing, Cowley, Glenn S., Weir, Barbara A., Boehm, Jesse S., Rusin, Scott, Scott, Justine A., East, Alexandra, Ali, Levi D., Lizotte, Patrick H., Wong, Terence C., Jiang, Guozhi, Hsiao, Jessica, Mermel, Craig H., Getz, Gad, Barretina, Jordi, Gopal, Shuba, Tamayo, Pablo, Gould, Joshua, Tsherniak, Aviad, Stransky, Nicolas, Luo, Biao, Ren, Yin, Drapkin, Ronny, Bhatia, Sangeeta N., Mesirov, Jill P., Garraway, Levi A., Meyerson, Matthew, Lander, Eric S., Root, David E., Hahn, William C.
منشور في 2011

Functional genomics reveals serine synthesis is essential in PHGDH-amplified breast cancer

بواسطة Possemato, Richard, Marks, Kevin M., Shaul, Yoav D., Pacold, Michael E., Kim, Dohoon, Birsoy, Kivanç, Sethumadhavan, Shalini, Woo, Hin-Koon, Jang, Hyun G., Jha, Abhishek K., Chen, Walter W., Barrett, Francesca G., Stransky, Nicolas, Tsun, Zhi-Yang, Cowley, Glenn S., Barretina, Jordi, Kalaany, Nada Y., Hsu, Peggy P., Ottina, Kathleen, Chan, Albert M., Yuan, Bingbing, Garraway, Levi A., Root, David E., Mino-Kenudson, Mari, Brachtel, Elena F., Driggers, Edward M., Sabatini, David M.
منشور في 2011

An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules

بواسطة Basu, Amrita, Bodycombe, Nicole E., Cheah, Jaime H., Price, Edmund V., Liu, Ke, Schaefer, Giannina I., Ebright, Richard Y., Stewart, Michelle L., Ito, Daisuke, Wang, Stephanie, Bracha, Abigail L., Liefeld, Ted, Wawer, Mathias, Gilbert, Joshua C., Wilson, Andrew J., Stransky, Nicolas, Kryukov, Gregory V., Dancik, Vlado, Barretina, Jordi, Garraway, Levi A., Hon, C. Suk-Yee, Munoz, Benito, Bittker, Joshua A., Stockwell, Brent R., Khabele, Dineo, Stern, Andrew M., Clemons, Paul A., Shamji, Alykhan F., Schreiber, Stuart L.
منشور في 2013

COT/MAP3K8 drives resistance to RAF inhibition through MAP kinase pathway reactivation

بواسطة Johannessen, Cory M., Boehm, Jesse S., Kim, So Young, Thomas, Sapana R., Wardwell, Leslie, Johnson, Laura A., Emery, Caroline M., Stransky, Nicolas, Cogdill, Alexandria P., Barretina, Jordi, Caponigro, Giordano, Hieronymus, Haley, Murray, Ryan R., Salehi-Ashtiani, Kourosh, Hill, David E., Vidal, Marc, Zhao, Jean J., Yang, Xiaoping, Alkan, Ozan, Kim, Sungjoon, Harris, Jennifer L., Wilson, Christopher J., Myer, Vic E., Finan, Peter M., Root, David E., Roberts, Thomas M., Golub, Todd, Flaherty, Keith T., Dummer, Reinhard, Weber, Barbara, Sellers, William R., Schlegel, Robert, Wargo, Jennifer A., Hahn, William C., Garraway, Levi A.
منشور في 2010

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

بواسطة Lohr, Jens G., Stojanov, Petar, Lawrence, Michael S., Auclair, Daniel, Chapuy, Bjoern, Sougnez, Carrie, Cruz-Gordillo, Peter, Knoechel, Birgit, Asmann, Yan W., Slager, Susan L., Novak, Anne J., Dogan, Ahmet, Ansell, Stephen M., Link, Brian K., Zou, Lihua, Gould, Joshua, Saksena, Gordon, Stransky, Nicolas, Rangel-Escareño, Claudia, Fernandez-Lopez, Juan Carlos, Hidalgo-Miranda, Alfredo, Melendez-Zajgla, Jorge, Hernández-Lemus, Enrique, Schwarz-Cruz y Celis, Angela, Imaz-Rosshandler, Ivan, Ojesina, Akinyemi I., Jung, Joonil, Pedamallu, Chandra S., Lander, Eric S., Habermann, Thomas M., Cerhan, James R., Shipp, Margaret A., Getz, Gad, Golub, Todd R.
منشور في 2012

Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion

بواسطة Bass, Adam J, Lawrence, Michael S, Brace, Lear E, Ramos, Alex H, Drier, Yotam, Cibulskis, Kristian, Sougnez, Carrie, Voet, Douglas, Saksena, Gordon, Sivachenko, Andrey, Jing, Rui, Parkin, Melissa, Pugh, Trevor, Verhaak, Roel G, Stransky, Nicolas, Boutin, Adam T, Barretina, Jordi, Solit, David B, Vakiani, Evi, Shao, Wenlin, Mishina, Yuji, Warmuth, Markus, Jimenez, Jose, Chiang, Derek Y, Signoretti, Sabina, Kaelin, William G, Spardy, Nicole, Hahn, William C, Hoshida, Yujin, Ogino, Shuji, DePinho, Ronald A, Chin, Lynda, Garraway, Levi A, Fuchs, Charles S, Baselga, Jose, Tabernero, Josep, Gabriel, Stacey, Lander, Eric S, Getz, Gad, Meyerson, Matthew
منشور في 2011

The Mutational Landscape of Head and Neck Squamous Cell Carcinoma

بواسطة Stransky, Nicolas, Egloff, Ann Marie, Tward, Aaron D., Kostic, Aleksandar D., Cibulskis, Kristian, Sivachenko, Andrey, Kryukov, Gregory V., Lawrence, Michael, Sougnez, Carrie, McKenna, Aaron, Shefler, Erica, Ramos, Alex H., Stojanov, Petar, Carter, Scott L., Voet, Douglas, Cortés, Maria L, Auclair, Daniel, Berger, Michael F., Saksena, Gordon, Guiducci, Candace, Onofrio, Robert, Parkin, Melissa, Romkes, Marjorie, Weissfeld, Joel L., Seethala, Raja R., Wang, Lin, Rangel-Escareño, Claudia, Fernandez-Lopez, Juan Carlos, Hidalgo-Miranda, Alfredo, Melendez-Zajgla, Jorge, Winckler, Wendy, Ardlie, Kristin, Gabriel, Stacey B., Meyerson, Matthew, Lander, Eric S., Getz, Gad, Golub, Todd R., Garraway, Levi A., Grandis, Jennifer R.
منشور في 2011

A Landscape of Driver Mutations in Melanoma

بواسطة Hodis, Eran, Watson, Ian R., Kryukov, Gregory V., Arold, Stefan T., Imielinski, Marcin, Theurillat, Jean-Philippe, Nickerson, Elizabeth, Auclair, Daniel, Li, Liren, Place, Chelsea, DiCara, Daniel, Ramos, Alex H., Lawrence, Michael S., Cibulskis, Kristian, Sivachenko, Andrey, Voet, Douglas, Saksena, Gordon, Stransky, Nicolas, Onofrio, Robert C., Winckler, Wendy, Ardlie, Kristin, Wagle, Nikhil, Wargo, Jennifer, Chong, Kelly, Morton, Donald L., Stemke-Hale, Katherine, Chen, Guo, Noble, Michael, Meyerson, Matthew, Ladbury, John E., Davies, Michael A., Gershenwald, Jeffrey E., Wagner, Stephan N., Hoon, Dave S.B., Schadendorf, Dirk, Lander, Eric S., Gabriel, Stacey B., Getz, Gad, Garraway, Levi A., Chin, Lynda
منشور في 2012