A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein

Members of the ETS transcription factor family have been implicated in several cancers, where they are often dysregulated by genomic derangement. ETS variant 1 (ETV1) is an ETS factor gene that undergoes chromosomal translocation in prostate cancers and Ewing's sarcomas, amplification in melano...

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Detaylı Bibliyografya
Asıl Yazarlar: Pop, Marius S, Stransky, Nicolas, Garvie, Colin W, Theurillat, Jean-Philippe, Lewis, Timothy A, Zhong, Cheng, Culyba, Elizabeth K, Lin, Fallon, Daniels, Douglas S, Pagliarini, Raymond, Ronco, Lucienne, Koehler, Angela N, Garraway, Levi A
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154495/
https://ncbi.nlm.nih.gov/pubmed/24737027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0689
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