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Small-Molecule Inhibitors of the Myc Oncoprotein

The c-Myc (Myc) oncoprotein is among the most attractive of cancer targets given that is deregulated in the majority of tumors and that its inhibition profoundly affects their growth and/or survival. However, its role as a seldom-mutated transcription factor, its lack of enzymatic activity for which...

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Detalhes bibliográficos
Main Authors: Fletcher, Steven, Prochownik, Edward V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4169356/
https://ncbi.nlm.nih.gov/pubmed/24657798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2014.03.005
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