Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activity

Interferon regulatory factor-3 (IRF-3) was found to specifically interact with HPV16 E6 in a yeast two-hybrid screen. IRF-3 is activated by the presence of double-stranded RNA or by virus infection to form a stable complex with other transcriptional regulators that bind to the regulatory elements of...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Ronco, Lucienne V., Karpova, Alla Y., Vidal, Marc, Howley, Peter M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 1998
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316980/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9649509/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.13.2061
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