Repression by Homeoprotein Pitx1 of Virus-Induced Interferon A Promoters Is Mediated by Physical Interaction and trans Repression of IRF3 and IRF7

Interferon A (IFN-A) genes are differentially expressed after virus induction. The differential expression of individual IFN-A genes is modulated by the specific transcription activators IFN regulatory factor 3 (IRF3) and IRF-7 and the homeoprotein transcription repressor Pitx1. We now show that rep...

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Detalhes bibliográficos
Main Authors: Island, Marie-Laure, Mesplede, Thibault, Darracq, Nicole, Bandu, Marie-Thérèse, Christeff, Nicolas, Djian, Philippe, Drouin, Jacques, Navarro, Sébastien
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Transcriptional Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC139826/
https://ncbi.nlm.nih.gov/pubmed/12242290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.20.7120-7133.2002
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