Inhibition of Histone Deacetylation Induces Constitutive Derepression of the Beta Interferon Promoter and Confers Antiviral Activity

The induction of alpha/beta interferon (IFN-α/β) genes constitutes one of the first responses of the cell to virus infection. The IFN-β gene is constitutively repressed in uninfected cells and is transiently activated after virus infection. In this work we demonstrate that histone deacetylation regu...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Shestakova, Elena, Bandu, Marie-Thérèse, Doly, Janine, Bonnefoy, Eliette
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114137/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238870/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.7.3444-3452.2001
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