Inhibition of Histone Deacetylation Induces Constitutive Derepression of the Beta Interferon Promoter and Confers Antiviral Activity

The induction of alpha/beta interferon (IFN-α/β) genes constitutes one of the first responses of the cell to virus infection. The IFN-β gene is constitutively repressed in uninfected cells and is transiently activated after virus infection. In this work we demonstrate that histone deacetylation regu...

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Hlavní autoři: Shestakova, Elena, Bandu, Marie-Thérèse, Doly, Janine, Bonnefoy, Eliette
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC114137/
https://ncbi.nlm.nih.gov/pubmed/11238870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.7.3444-3452.2001
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