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Inhibition of Histone Deacetylation Induces Constitutive Derepression of the Beta Interferon Promoter and Confers Antiviral Activity
The induction of alpha/beta interferon (IFN-α/β) genes constitutes one of the first responses of the cell to virus infection. The IFN-β gene is constitutively repressed in uninfected cells and is transiently activated after virus infection. In this work we demonstrate that histone deacetylation regu...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2001
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC114137/ https://ncbi.nlm.nih.gov/pubmed/11238870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.7.3444-3452.2001 |
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