B-cell depletion in SLE: clinical and trial experience with rituximab and ocrelizumab and implications for study design

le Reddy, Venkat, Jayne, David, Close, David, Isenberg, David
Foilsithe 2013

Reductive Damage in Directly Ionized DNA: Saturation of the C5=C6 Bond of Cytosine in d(CGCG)(2) Crystals

le Debije, Michael G., Close, David M., Bernhard, William A.
Foilsithe 2002

High Content Screening Characterization of Head and Neck Squamous Cell Carcinoma Multicellular Tumor Spheroid Cultures Generated in 384-Well Ultra-Low Attachment Plates to Screen f...

le Kochanek, Stanton J., Close, David A., Johnston, Paul A.
Foilsithe in Assay Drug Dev Technol (2019)

Reply to Thornton and Carroll: Lamprey possess a highly specific corticosteroid signaling system

le Close, David A., Yun, Sang-Seon, McCormick, Stephen D.
Foilsithe 2011

One-electron oxidation of ds(5’-GGG-3’) and ds(5’-G(8OG)G-3’) and the nature of hole distribution: A density functional theory (DFT) study

le Kumar, Anil, Adhikary, Amitava, Sevilla, Michael D., Close, David M.
Foilsithe in Phys Chem Chem Phys (2020)

High-Content Screening Comparison of Cancer Drug Accumulation and Distribution in Two-Dimensional and Three-Dimensional Culture Models of Head and Neck Cancer

le Shan, Feng, Close, David A., Camarco, Daniel P., Johnston, Paul A.
Foilsithe in Assay Drug Dev Technol (2018)

Production of Uniform 3D Microtumors in Hydrogel Microwell Arrays for Measurement of Viability, Morphology, and Signaling Pathway Activation

le Singh, Manjulata, Close, David A., Mukundan, Shilpaa, Johnston, Paul A., Sant, Shilpa
Foilsithe in Assay Drug Dev Technol (2015)

Maximizing the Value of Cancer Drug Screening in Multicellular Tumor Spheroid Cultures: A Case Study in Five Head and Neck Squamous Cell Carcinoma Cell Lines.

le Kochanek, Stanton J., Close, David A., Camarco, Daniel P., Johnston, Paul A.
Foilsithe in SLAS Discov (2020)

11-Deoxycortisol is a corticosteroid hormone in the lamprey

le Close, David A., Yun, Sang-Seon, McCormick, Stephen D., Wildbill, Andrew J., Li, Weiming
Foilsithe 2010

Projected Scenarios for Coastal First Nations’ Fisheries Catch Potential under Climate Change: Management Challenges and Opportunities

le Weatherdon, Lauren V., Ota, Yoshitaka, Jones, Miranda C., Close, David A., Cheung, William W. L.
Foilsithe in PLoS One (2016)

Unbiased high throughput drug combination pilot screen identifies synergistic drug combinations effective against patient-derived and drug-resistant melanoma cell lines.

le Close, David A., Kirkwood, John M., Fecek, Ronald J., Storkus, Walter J., Johnston, Paul A.
Foilsithe in SLAS Discov (2020)

Reconfiguring the AR-TIF2 Protein–Protein Interaction HCS Assay in Prostate Cancer Cells and Characterizing the Hits from a LOPAC Screen

le Fancher, Ashley T., Hua, Yun, Camarco, Daniel P., Close, David A., Strock, Christopher J., Johnston, Paul A.
Foilsithe in Assay Drug Dev Technol (2016)

High-Content Screening Campaign to Identify Compounds That Inhibit or Disrupt Androgen Receptor-Transcriptional Intermediary Factor 2 Protein-Protein Interactions for the Treatment...

le Fancher, Ashley T., Hua, Yun, Camarco, Daniel P., Close, David A., Strock, Christopher J., Johnston, Paul A.
Foilsithe in Assay Drug Dev Technol (2018)

Pharmacodynamic biomarkers and differential effects of TNF‐ and GM‐CSF‐targeting biologics in rheumatoid arthritis

le Guo, Xiang, Wang, Shiliang, Godwood, Alex, Close, David, Ryan, Patricia C., Roskos, Lorin K., White, Wendy I.
Foilsithe in Int J Rheum Dis (2018)

Discovery of Non-peptide Small Molecule Allosteric Modulators of the Src-family Kinase, Hck

le Dorman, Heather R., Close, David, Wingert, Bentley M., Camacho, Carlos J., Johnston, Paul A., Smithgall, Thomas E.
Foilsithe in Front Chem (2019)

Design and activity of AP endonuclease-1 inhibitors

le Feng, Zhiwei, Kochanek, Stanton, Close, David, Wang, LiRong, Srinivasan, Ajay, Almehizia, Abdulrahman A., Iyer, Prema, Xie, Xiang-Qun, Johnston, Paul A., Gold, Barry
Foilsithe in J Chem Biol (2015)

Pharmacokinetics, pharmacodynamics and safety of the inverse retinoic acid‐related orphan receptor γ agonist AZD0284

le Asimus, Sara, Palmér, Robert, Albayaty, Muna, Forsman, Henrik, Lundin, Christina, Olsson, Marita, Pehrson, Rikard, Mo, John, Russell, Muir, Carlert, Sara, Close, David, Keeling, David
Foilsithe in Br J Clin Pharmacol (2020)

Discovery of Diverse Small Molecule Chemotypes with Cell-Based PKD1 Inhibitory Activity

le Sharlow, Elizabeth R., Mustata Wilson, Gabriela, Close, David, Leimgruber, Stephanie, Tandon, Manuj, Reed, Robyn B., Shun, Tong Ying, Wang, Q. Jane, Wipf, Peter, Lazo, John S.
Foilsithe 2011

Identification of Potent Chemotypes Targeting Leishmania major Using a High-Throughput, Low-Stringency, Computationally Enhanced, Small Molecule Screen

le Sharlow, Elizabeth R., Close, David, Shun, Tongying, Leimgruber, Stephanie, Reed, Robyn, Mustata, Gabriela, Wipf, Peter, Johnson, Jacob, O'Neil, Michael, Grögl, Max, Magill, Alan J., Lazo, John S.
Foilsithe 2009

A Target-Based High Throughput Screen Yields Trypanosoma brucei Hexokinase Small Molecule Inhibitors with Antiparasitic Activity

le Sharlow, Elizabeth R., Lyda, Todd A., Dodson, Heidi C., Mustata, Gabriela, Morris, Meredith T., Leimgruber, Stephanie S., Lee, Kuo-Hsiung, Kashiwada, Yoshiki, Close, David, Lazo, John S., Morris, James C.
Foilsithe 2010