High-Content Positional Biosensor Screening Assay for Compounds to Prevent or Disrupt Androgen Receptor and Transcriptional Intermediary Factor 2 Protein–Protein Interactions

Por Hua, Yun, Shun, Tong Ying, Strock, Christopher J., Johnston, Paul A.
Publicado em 2014

The Microphysiology Systems Database for Analyzing and Modeling Compound Interactions with Human and Animal Organ Models

Por Gough, Albert, Vernetti, Lawrence, Bergenthal, Luke, Shun, Tong Ying, Taylor, D. Lansing
Publicado no Appl In Vitro Toxicol (2016)

Identification of Chemosensitivity Nodes for Vinblastine through Small Interfering RNA High-Throughput Screens

Por Kitchens, Carolyn A., McDonald, Peter R., Shun, Tong Ying, Pollack, Ian F., Lazo, John S.
Publicado em 2011

Development and Validation of a High-Content Screening Assay to Identify Inhibitors of Cytoplasmic Dynein-Mediated Transport of Glucocorticoid Receptor to the Nucleus

Por Johnston, Paul A., Shinde, Sunita N., Hua, Yun, Shun, Tong Ying, Lazo, John S., Day, Billy W.
Publicado em 2012

High-Content pSTAT3/1 Imaging Assays to Screen for Selective Inhibitors of STAT3 Pathway Activation in Head and Neck Cancer Cell Lines

Por Johnston, Paul A., Sen, Malabika, Hua, Yun, Camarco, Daniel, Shun, Tong Ying, Lazo, John S., Grandis, Jennifer R.
Publicado em 2014

Identification of Survival Genes in Human Glioblastoma Cells by Small Interfering RNA Screening

Por Thaker, Nikhil G., Zhang, Fang, McDonald, Peter R., Shun, Tong Ying, Lewen, Michael D., Pollack, Ian F., Lazo, John S.
Publicado em 2009

Profiling the NIH Small Molecule Repository for Compounds That Generate H(2)O(2) by Redox Cycling in Reducing Environments

Por Soares, Karina M., Blackmon, Nicole, Shun, Tong Ying, Shinde, Sunita N., Takyi, Harold K., Wipf, Peter, Lazo, John S., Johnston, Paul A.
Publicado em 2010

Development of a 384-Well Colorimetric Assay to Quantify Hydrogen Peroxide Generated by the Redox Cycling of Compounds in the Presence of Reducing Agents

Por Johnston, Paul A., Soares, Karina M., Shinde, Sunita N., Foster, Caleb A., Shun, Tong Ying, Takyi, Harold K., Wipf, Peter, Lazo, John S.
Publicado em 2008

Cdc25B Dual-Specificity Phosphatase Inhibitors Identified in a High-Throughput Screen of the NIH Compound Library

Por Johnston, Paul A., Foster, Caleb A., Tierno, Marni Brisson, Shun, Tong Ying, Shinde, Sunita N., Paquette, William D., Brummond, Kay M., Wipf, Peter, Lazo, John S.
Publicado em 2009

Discovery of Diverse Small Molecule Chemotypes with Cell-Based PKD1 Inhibitory Activity

Por Sharlow, Elizabeth R., Mustata Wilson, Gabriela, Close, David, Leimgruber, Stephanie, Tandon, Manuj, Reed, Robyn B., Shun, Tong Ying, Wang, Q. Jane, Wipf, Peter, Lazo, John S.
Publicado em 2011

Characterization and Optimization of a Novel Protein–Protein Interaction Biosensor High-Content Screening Assay to Identify Disruptors of the Interactions Between p53 and hDM2

Por Dudgeon, Drew D., Shinde, Sunita N., Shun, Tong Ying, Lazo, John S., Strock, Christopher J., Giuliano, Kenneth A., Taylor, D. Lansing, Johnston, Patricia A., Johnston, Paul A.
Publicado em 2010

HCS Campaign to Identify Selective Inhibitors of IL-6-Induced STAT3 Pathway Activation in Head and Neck Cancer Cell Lines

Por Johnston, Paul A., Sen, Malabika, Hua, Yun, Camarco, Daniel P., Shun, Tong Ying, Lazo, John S., Wilson, Gabriela Mustata, Resnick, Lynn O., LaPorte, Matthew G., Wipf, Peter, Huryn, Donna M., Grandis, Jennifer R.
Publicado no Assay Drug Dev Technol (2015)

Automated High-Content Live Animal Drug Screening Using C. elegans Expressing the Aggregation Prone Serpin α1-antitrypsin Z

Por Gosai, Sager J., Kwak, Joon Hyeok, Luke, Cliff J., Long, Olivia S., King, Dale E., Kovatch, Kevin J., Johnston, Paul A., Shun, Tong Ying, Lazo, John S., Perlmutter, David H., Silverman, Gary A., Pak, Stephen C.
Publicado em 2010

Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans

Por Bhushan, Abhinav, Senutovitch, Nina, Bale, Shyam S, McCarty, William J, Hegde, Manjunath, Jindal, Rohit, Golberg, Inna, Berk Usta, O, Yarmush, Martin L, Vernetti, Lawrence, Gough, Albert, Bakan, Ahmet, Shun, Tong Ying, Biasio, Richard, Lansing Taylor, D
Publicado em 2013

Identifying and Quantifying Heterogeneity in High Content Analysis: Application of Heterogeneity Indices to Drug Discovery

Por Gough, Albert H., Chen, Ning, Shun, Tong Ying, Lezon, Timothy R., Boltz, Robert C., Reese, Celeste E., Wagner, Jacob, Vernetti, Lawrence A., Grandis, Jennifer R., Lee, Adrian V., Stern, Andrew M., Schurdak, Mark E., Taylor, D. Lansing
Publicado em 2014

In Vitro Platforms for Evaluating Liver Toxicity

Por Bale, Shyam Sundhar, Vernetti, Lawrence, Senutovitch, Nina, Jindal, Rohit, Hegde, Manjunath, Gough, Albert, McCarty, William J, Bakan, Ahmet, Bhushan, Abhinav, Shun, Tong Ying, Golberg, Inna, DeBiasio, Richard, Usta, Berk Osman, Taylor, D. Lansing, Yarmush, Martin L.
Publicado em 2014

Alkylation sensitivity screens reveal a conserved cross-species functionome

Por Svilar, David, Dyavaiah, Madhu, Brown, Ashley R., Tang, Jiang-bo, Li, Jianfeng, McDonald, Peter R., Shun, Tong Ying, Braganza, Andrea, Wang, Xiao-hong, Maniar, Salony, St Croix, Claudette M., Lazo, John S., Pollack, Ian F., Begley, Thomas J., Sobol, Robert W.
Publicado em 2012