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High-Content Positional Biosensor Screening Assay for Compounds to Prevent or Disrupt Androgen Receptor and Transcriptional Intermediary Factor 2 Protein–Protein Interactions

The androgen receptor–transcriptional intermediary factor 2 (AR-TIF2) positional protein–protein interaction (PPI) biosensor assay described herein combines physiologically relevant cell-based assays with the specificity of binding assays by incorporating structural information of AR and TIF2 functi...

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Autors principals: Hua, Yun, Shun, Tong Ying, Strock, Christopher J., Johnston, Paul A.
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4146499/
https://ncbi.nlm.nih.gov/pubmed/25181412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2014.594
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