HCS Campaign to Identify Selective Inhibitors of IL-6-Induced STAT3 Pathway Activation in Head and Neck Cancer Cell Lines

Signal transducer and activator of transcription factor 3 (STAT3) is hyperactivated in head and neck squamous cell carcinomas (HNSCC). Cumulative evidence indicates that IL-6 production by HNSCC cells and/or stromal cells in the tumor microenvironment activates STAT3 and contributes to tumor progres...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Assay Drug Dev Technol
Päätekijät: Johnston, Paul A., Sen, Malabika, Hua, Yun, Camarco, Daniel P., Shun, Tong Ying, Lazo, John S., Wilson, Gabriela Mustata, Resnick, Lynn O., LaPorte, Matthew G., Wipf, Peter, Huryn, Donna M., Grandis, Jennifer R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Mary Ann Liebert, Inc. 2015
Aiheet:
Original Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556090/
https://ncbi.nlm.nih.gov/pubmed/26317883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2015.663
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