HCS Campaign to Identify Selective Inhibitors of IL-6-Induced STAT3 Pathway Activation in Head and Neck Cancer Cell Lines

Signal transducer and activator of transcription factor 3 (STAT3) is hyperactivated in head and neck squamous cell carcinomas (HNSCC). Cumulative evidence indicates that IL-6 production by HNSCC cells and/or stromal cells in the tumor microenvironment activates STAT3 and contributes to tumor progres...

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Detalhes bibliográficos
Publicado no:Assay Drug Dev Technol
Main Authors: Johnston, Paul A., Sen, Malabika, Hua, Yun, Camarco, Daniel P., Shun, Tong Ying, Lazo, John S., Wilson, Gabriela Mustata, Resnick, Lynn O., LaPorte, Matthew G., Wipf, Peter, Huryn, Donna M., Grandis, Jennifer R.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556090/
https://ncbi.nlm.nih.gov/pubmed/26317883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2015.663
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