Identifying and Quantifying Heterogeneity in High Content Analysis: Application of Heterogeneity Indices to Drug Discovery

One of the greatest challenges in biomedical research, drug discovery and diagnostics is understanding how seemingly identical cells can respond differently to perturbagens including drugs for disease treatment. Although heterogeneity has become an accepted characteristic of a population of cells, i...

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Detalhes bibliográficos
Main Authors: Gough, Albert H., Chen, Ning, Shun, Tong Ying, Lezon, Timothy R., Boltz, Robert C., Reese, Celeste E., Wagner, Jacob, Vernetti, Lawrence A., Grandis, Jennifer R., Lee, Adrian V., Stern, Andrew M., Schurdak, Mark E., Taylor, D. Lansing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4103836/
https://ncbi.nlm.nih.gov/pubmed/25036749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0102678
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