Towards a three-dimensional microfluidic liver platform for predicting drug efficacy and toxicity in humans

Although the process of drug development requires efficacy and toxicity testing in animals prior to human testing, animal models have limited ability to accurately predict human responses to xenobiotics and other insults. Societal pressures are also focusing on reduction of and, ultimately, replacem...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Bhushan, Abhinav, Senutovitch, Nina, Bale, Shyam S, McCarty, William J, Hegde, Manjunath, Jindal, Rohit, Golberg, Inna, Berk Usta, O, Yarmush, Martin L, Vernetti, Lawrence, Gough, Albert, Bakan, Ahmet, Shun, Tong Ying, Biasio, Richard, Lansing Taylor, D
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2013
Aiheet:
Review
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028964/
https://ncbi.nlm.nih.gov/pubmed/24565476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt377
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