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Dynamic Interplay of Flow and Collagen Stabilizes Primary Hepatocytes Culture in a Microfluidic Platform

The creation of stable flow cultures of hepatocytes is highly desirable for the development of platforms for drug toxicity screening, bio-artificial liver support devices, and models for investigating liver physiology and pathophysiology. Given that hepatocytes cultured using the collagen overlay or...

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Autores principales: Hegde, Manjunath, Jindal, Rohit, Bhushan, Abhinav, Bale, Shyam Sundhar, McCarty, William J, Golberg, Inna, Usta, O. Berk, Yarmush, Martin L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036071/
https://ncbi.nlm.nih.gov/pubmed/24770663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4lc00071d
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