The multi-faceted roles of the PI3K-AKT pathway in melanoma

Por Davies, Michael A
Publicado no J Transl Med (2015)

Targeted Therapy for Melanoma - A Primer

Por Davies, Michael A., Gershenwald, Jeffrey E.
Publicado em 2011

Navigating the Therapeutic Complexity of PI3K Pathway Inhibition in Melanoma

Por Kwong, Lawrence N., Davies, Michael A.
Publicado em 2013

Targeting KIT in Melanoma: A Paradigm of Molecular Medicine and Targeted Therapeutics

Por Woodman, Scott E., Davies, Michael A.
Publicado em 2010

Genotyping of cutaneous melanoma

Por Glitza, Isabella C., Davies, Michael A.
Publicado no Chin Clin Oncol (2014)

Converting biology into clinical benefit: lessons learned from BRAF inhibitors

Por McQuade, Jennifer, Davies, Michael A
Publicado no Melanoma Manag (2015)

Melanoma brain metastases: current areas of investigation and future directions

Por Oliva, Isabella Glitza, Tawbi, Hussein, Davies, Michael A.
Publicado no Cancer J (2017)

New Strategies in Melanoma: Molecular Testing in Advanced Disease

Por Woodman, Scott E., Lazar, Alexander J., Aldape, Kenneth D., Davies, Michael A.
Publicado em 2012

RAC1 P29S regulates PD-L1 expression in melanoma

Por Vu, Ha Linh, Rosenbaum, Sheera, Purwin, Timothy J., Davies, Michael A., Aplin, Andrew E.
Publicado no Pigment Cell Melanoma Res (2015)

Function-blocking ERBB3 antibody inhibits the adaptive response to RAF inhibitor

Por Kugel, Curtis H., Hartsough, Edward J., Davies, Michael A., Setiady, Yulius Y., Aplin, Andrew E.
Publicado em 2014

Association of Activated c-Met with NRAS-Mutated Human Melanomas: A Possible Avenue for Targeting

Por Chattopadhyay, Chandrani, Ellerhorst, Julie A., Ekmekcioglu, Suhendan, Greene, Victoria R., Davies, Michael A., Grimm, Elizabeth A.
Publicado em 2012

Tissue Resources for Clinical Use and Marker Studies in Melanoma

Por Curry, Jonathan L., Davies, Michael A., Calderone, Tiffany L., Nathanson, Katherine, Prieto, Victor G., Gershenwald, Jeffrey E.
Publicado no Methods Mol Biol (2014)

Pathways and therapeutic targets in melanoma

Por Shtivelman, Emma, Davies, Michael A., Hwu, Patrick, Yang, James, Lotem, Michal, Oren, Moshe, Flaherty, Keith T., Fisher, David E.
Publicado em 2014

Combination Small Molecule MEK and PI3K Inhibition Enhances Uveal Melanoma Cell Death in a Mutant GNAQ and GNA11 Dependent Manner

Por Khalili, Jahan S., Yu, Xiaoxing, Wang, Ji, Hayes, Brendan C., Davies, Michael A., Lizee, Gregory, Esmaeli, Bita, Woodman, Scott E.
Publicado em 2012

Basal and treatment-induced activation of AKT mediates resistance to cell death by AZD6244 (ARRY-142886) in Braf-mutant human cutaneous melanoma cells

Por Gopal, Y.N. Vashisht, Deng, Wanleng, Woodman, Scott E., Komurov, Kakajan, Ram, Prahlad, Smith, Paul D., Davies, Michael A.
Publicado no Cancer Res (2010)

BAYESIAN SPARSE GRAPHICAL MODELS FOR CLASSIFICATION WITH APPLICATION TO PROTEIN EXPRESSION DATA

Por Baladandayuthapani, Veerabhadran, Talluri, Rajesh, Ji, Yuan, Coombes, Kevin R., Lu, Yiling, Hennessy, Bryan T., Davies, Michael A., Mallick, Bani K.
Publicado no Ann Appl Stat (2014)

MIG6 is MEK-regulated and affects EGF-induced migration in mutant NRAS melanoma

Por Vu, Ha Linh, Rosenbaum, Sheera, Capparelli, Claudia, Purwin, Timothy J., Davies, Michael A., Berger, Adam C., Aplin, Andrew E.
Publicado no J Invest Dermatol (2015)

Somatic Copy Number Alterations at Oncogenic Loci Show Diverse Correlations with Gene Expression

Por Roszik, Jason, Wu, Chang-Jiun, Siroy, Alan E., Lazar, Alexander J., Davies, Michael A, Woodman, Scott E, Kwong, Lawrence N
Publicado no Sci Rep (2016)

An in vivo reporter to quantitatively and temporally analyze the effects of CDK4/6 inhibitor-based therapies in melanoma

Por Teh, Jessica L.F., Purwin, Timothy J., Greenawalt, Evan J., Chervoneva, Inna, Goldberg, Allison, Davies, Michael A., Aplin, Andrew E.
Publicado no Cancer Res (2016)

Physical Association of PDK1 with AKT1 Is Sufficient for Pathway Activation Independent of Membrane Localization and Phosphatidylinositol 3 Kinase

Por Ding, Zhiyong, Liang, Jiyong, Li, Jin, Lu, Yiling, Ariyaratna, Vathsala, Lu, Zhimin, Davies, Michael A., Westwick, John K., Mills, Gordon B.
Publicado em 2010