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Converting biology into clinical benefit: lessons learned from BRAF inhibitors

The identification and pharmacological targeting of activating BRAF mutations in melanoma has led to significant improvements in patient outcomes. This perspective paper illustrates the lessons learned from the study of BRAF mutations and the development of BRAF inhibitors. The relevance of these le...

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Pubblicato in:Melanoma Manag
Autori principali: McQuade, Jennifer, Davies, Michael A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Future Medicine Ltd 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649930/
https://ncbi.nlm.nih.gov/pubmed/26594316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/mmt.15.18
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