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Converting biology into clinical benefit: lessons learned from BRAF inhibitors

The identification and pharmacological targeting of activating BRAF mutations in melanoma has led to significant improvements in patient outcomes. This perspective paper illustrates the lessons learned from the study of BRAF mutations and the development of BRAF inhibitors. The relevance of these le...

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Publicado en:Melanoma Manag
Main Authors: McQuade, Jennifer, Davies, Michael A
Formato: Artigo
Idioma:Inglês
Publicado: Future Medicine Ltd 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4649930/
https://ncbi.nlm.nih.gov/pubmed/26594316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/mmt.15.18
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