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BRAF inhibitors in clinical oncology

Activating mutations of the BRAF oncogene are present in approximately 5-10% of all human malignancies and lead to constitutive activation of the mitogen activated protein kinase (MAPK) pathway. The introduction of BRAF inhibitors has greatly improved the short term prospects of some patients with t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Morris, Van, Kopetz, Scott
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Faculty of 1000 Ltd 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3619157/
https://ncbi.nlm.nih.gov/pubmed/23585929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12703/P5-11
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