Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer

Por Cheung, Hiu Wing, Cowley, Glenn S., Weir, Barbara A., Boehm, Jesse S., Rusin, Scott, Scott, Justine A., East, Alexandra, Ali, Levi D., Lizotte, Patrick H., Wong, Terence C., Jiang, Guozhi, Hsiao, Jessica, Mermel, Craig H., Getz, Gad, Barretina, Jordi, Gopal, Shuba, Tamayo, Pablo, Gould, Joshua, Tsherniak, Aviad, Stransky, Nicolas, Luo, Biao, Ren, Yin, Drapkin, Ronny, Bhatia, Sangeeta N., Mesirov, Jill P., Garraway, Levi A., Meyerson, Matthew, Lander, Eric S., Root, David E., Hahn, William C.
Publicado em 2011

Genomic copy number dictates a gene-independent cell response to CRISPR-Cas9 targeting

Por Aguirre, Andrew J., Meyers, Robin M., Weir, Barbara A., Vazquez, Francisca, Zhang, Cheng-Zhong, Ben-David, Uri, Cook, April, Ha, Gavin, Harrington, William F., Doshi, Mihir B., Kost-Alimova, Maria, Gill, Stanley, Xu, Han, Ali, Levi D., Jiang, Guozhi, Pantel, Sasha, Lee, Yenarae, Goodale, Amy, Cherniack, Andrew D., Oh, Coyin, Kryukov, Gregory, Cowley, Glenn S., Garraway, Levi A., Stegmaier, Kimberly, Roberts, Charles W., Golub, Todd R., Meyerson, Matthew, Root, David E., Tsherniak, Aviad, Hahn, William C.
Publicado no Cancer Discov (2016)

Computational correction of copy-number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells

Por Meyers, Robin M., Bryan, Jordan G., McFarland, James M., Weir, Barbara A., Sizemore, Ann E., Xu, Han, Dharia, Neekesh V., Montgomery, Phillip G., Cowley, Glenn S., Pantel, Sasha, Goodale, Amy, Lee, Yenarae, Ali, Levi D., Jiang, Guozhi, Lubonja, Rakela, Harrington, William F., Strickland, Matthew, Wu, Ting, Hawes, Derek C., Zhivich, Victor A., Wyatt, Meghan R., Kalani, Zohra, Chang, Jaime J., Okamoto, Michael, Stegmaier, Kimberly, Golub, Todd R., Boehm, Jesse S., Vazquez, Francisca, Root, David E., Hahn, William C., Tsherniak, Aviad
Publicado no Nat Genet (2017)

CRISPR-Cas9 screen reveals a MYCN-amplified neuroblastoma dependency on EZH2

Por Chen, Liying, Alexe, Gabriela, Dharia, Neekesh V., Ross, Linda, Iniguez, Amanda Balboni, Conway, Amy Saur, Wang, Emily Jue, Veschi, Veronica, Lam, Norris, Qi, Jun, Gustafson, W. Clay, Nasholm, Nicole, Vazquez, Francisca, Weir, Barbara A., Cowley, Glenn S., Ali, Levi D., Pantel, Sasha, Jiang, Guozhi, Harrington, William F., Lee, Yenarae, Goodale, Amy, Lubonja, Rakela, Krill-Burger, John M., Meyers, Robin M., Tsherniak, Aviad, Root, David E., Bradner, James E., Golub, Todd R., Roberts, Charles W.M., Hahn, William C., Weiss, William A., Thiele, Carol J., Stegmaier, Kimberly
Publicado no J Clin Invest (2017)

Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies

Por Cowley, Glenn S, Weir, Barbara A, Vazquez, Francisca, Tamayo, Pablo, Scott, Justine A, Rusin, Scott, East-Seletsky, Alexandra, Ali, Levi D, Gerath, William F.J, Pantel, Sarah E, Lizotte, Patrick H, Jiang, Guozhi, Hsiao, Jessica, Tsherniak, Aviad, Dwinell, Elizabeth, Aoyama, Simon, Okamoto, Michael, Harrington, William, Gelfand, Ellen, Green, Thomas M, Tomko, Mark J, Gopal, Shuba, Wong, Terence C, Li, Hubo, Howell, Sara, Stransky, Nicolas, Liefeld, Ted, Jang, Dongkeun, Bistline, Jonathan, Meyers, Barbara Hill, Armstrong, Scott A, Anderson, Ken C, Stegmaier, Kimberly, Reich, Michael, Pellman, David, Boehm, Jesse S, Mesirov, Jill P, Golub, Todd R, Root, David E, Hahn, William C
Publicado no Sci Data (2014)

Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies

Por Cowley, Glenn S, Weir, Barbara A, Vazquez, Francisca, Tamayo, Pablo, Scott, Justine A, Rusin, Scott, East-Seletsky, Alexandra, Ali, Levi D, Gerath, William FJ, Pantel, Sarah E, Lizotte, Patrick H, Jiang, Guozhi, Hsiao, Jessica, Tsherniak, Aviad, Dwinell, Elizabeth, Aoyama, Simon, Okamoto, Michael, Harrington, William, Gelfand, Ellen, Green, Thomas M, Tomko, Mark J, Gopal, Shuba, Wong, Terence C, Li, Hubo, Howell, Sara, Stransky, Nicolas, Liefeld, Ted, Jang, Dongkeun, Bistline, Jonathan, Hill Meyers, Barbara, Armstrong, Scott A, Anderson, Ken C, Stegmaier, Kimberly, Reich, Michael, Pellman, David, Boehm, Jesse S, Mesirov, Jill P, Golub, Todd R, Root, David E, Hahn, William C
Publicado no Sci Data (2014)