Zinc finger transcription factor CASZ1 interacts with histones, DNA repair proteins and recruits NuRD complex to regulate gene transcription

Por Liu, Zhihui, Lam, Norris, Thiele, Carol J.
Publicado no Oncotarget (2015)

Inhibition of STAT3 with the generation 2.5 antisense oligonucleotide, AZD9150, decreases neuroblastoma tumorigenicity and increases chemosensitivity

Por Odate, Seiichi, Veschi, Veronica, Yan, Shuang, Lam, Norris, Woessner, Richard, Thiele, Carol J.
Publicado no Clin Cancer Res (2016)

Identification of CASZ1 nuclear export signal (NES) reveals potential mechanisms for loss of CASZ1 tumor suppressor activity in neuroblastoma

Por Liu, Zhihui, Lam, Norris, Wang, Evelyn, Virden, Ryan A., Pawel, Bruce, Attiyeh, Edward F., Maris, John M., Thiele, Carol J.
Publicado no Oncogene (2016)

Epigenetic siRNA and chemical screens identify SETD8 inhibition as a therapeutic strategy for p53 activation in high-risk Neuroblastoma

Por Veschi, Veronica, Liu, Zhihui, Voss, Ty C., Ozbun, Laurent, Gryder, Berkley, Yan, Chunhua, Hu, Ying, Ma, Anqi, Jin, Jian, Mazur, Sharlyn J., Lam, Norris, Souza, Barbara K., Giannini, Giuseppe, Hager, Gordon L., Arrowsmith, Cheryl H., Khan, Javed, Appella, Ettore, Thiele, Carol J.
Publicado no Cancer Cell (2017)