Identification of CASZ1 nuclear export signal (NES) reveals potential mechanisms for loss of CASZ1 tumor suppressor activity in neuroblastoma

As a transcription factor, localization to the nucleus and the recruitment of co-factors to regulate gene transcription is essential. Nuclear localization and nucleosome remodeling and histone deacetylase (NuRD) complex binding are required for the zinc finger transcription factor CASZ1 to function...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Liu, Zhihui, Lam, Norris, Wang, Evelyn, Virden, Ryan A., Pawel, Bruce, Attiyeh, Edward F., Maris, John M., Thiele, Carol J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5140774/
https://ncbi.nlm.nih.gov/pubmed/27270431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.179
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