ATARiS: Computational quantification of gene suppression phenotypes from multisample RNAi screens

Genome-scale RNAi libraries enable the systematic interrogation of gene function. However, the interpretation of RNAi screens is complicated by the observation that RNAi reagents designed to suppress the mRNA transcripts of the same gene often produce a spectrum of phenotypic outcomes due to differe...

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Detaylı Bibliyografya
Asıl Yazarlar: Shao, Diane D., Tsherniak, Aviad, Gopal, Shuba, Weir, Barbara A., Tamayo, Pablo, Stransky, Nicolas, Schumacher, Steven E., Zack, Travis I., Beroukhim, Rameen, Garraway, Levi A., Margolin, Adam A., Root, David E., Hahn, William C., Mesirov, Jill P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2013
Konular:
Method
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3613583/
https://ncbi.nlm.nih.gov/pubmed/23269662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.143586.112
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