GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers

Por Mermel, Craig H, Schumacher, Steven E, Hill, Barbara, Meyerson, Matthew L, Beroukhim, Rameen, Getz, Gad
Publicado em 2011

Pan-Cancer Analysis Links PARK2 to BCL-XL-Dependent Control of Apoptosis

Por Gong, Yongxing, Schumacher, Steven E., Wu, Wei H., Tang, Fanying, Beroukhim, Rameen, Chan, Timothy A.
Publicado no Neoplasia (2016)

Genetic and Functional Studies Implicate HIF1α as a 14q Kidney Cancer Suppressor Gene

Por Shen, Chuan, Beroukhim, Rameen, Schumacher, Steven E., Zhou, Jing, Chang, Michelle, Signoretti, Sabina, Kaelin, William G.
Publicado em 2011

Somatic copy number alterations in gastric adenocarcinomas among Asian and Western patients

Por Schumacher, Steven E., Shim, Byoung Yong, Corso, Giovanni, Ryu, Min-Hee, Kang, Yoon-Koo, Roviello, Franco, Saksena, Gordon, Peng, Shouyong, Shivdasani, Ramesh A., Bass, Adam J., Beroukhim, Rameen
Publicado no PLoS One (2017)

Tumor suppressor genes that escape from X-inactivation contribute to cancer sex bias

Por Dunford, Andrew, Weinstock, David M., Savova, Virginia, Schumacher, Steven E., Cleary, John P., Yoda, Akinori, Sullivan, Timothy J., Hess, Julian M., Gimelbrant, Alexander A., Beroukhim, Rameen, Lawrence, Michael S., Getz, Gad, Lane, Andrew A.
Publicado no Nat Genet (2016)

Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins

Por Gong, Yongxing, Zack, Travis Ian, Morris, Luc G T, Lin, Kan, Hukkelhoven, Ellen, Raheja, Radhika, Tan, I-Li, Turcan, Sevin, Veeriah, Selvaraju, Meng, Shasha, Viale, Agnes, Schumacher, Steven E, Palmedo, Perry, Beroukhim, Rameen, Chan, Timothy A
Publicado no Nat Genet (2014)

MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism that Mimics the Role of Activated RAS in Malignancy

Por Neupane, Manish, Clark, Allison P., Landini, Serena, Birkbak, Nicolai J., Eklund, Aron C., Lim, Elgene, Culhane, Aedin C., Barry, William T., Schumacher, Steven E., Beroukhim, Rameen, Szallasi, Zoltan, Vidal, Marc, Hill, David E., Silver, Daniel P.
Publicado no Cancer Discov (2015)

ATARiS: Computational quantification of gene suppression phenotypes from multisample RNAi screens

Por Shao, Diane D., Tsherniak, Aviad, Gopal, Shuba, Weir, Barbara A., Tamayo, Pablo, Stransky, Nicolas, Schumacher, Steven E., Zack, Travis I., Beroukhim, Rameen, Garraway, Levi A., Margolin, Adam A., Root, David E., Hahn, William C., Mesirov, Jill P.
Publicado em 2013

Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth

Por Holst, Frederik, Hoivik, Erling A., Gibson, William J., Taylor-Weiner, Amaro, Schumacher, Steven E., Asmann, Yan W., Grossmann, Patrick, Trovik, Jone, Necela, Brian M., Thompson, E. Aubrey, Meyerson, Matthew, Beroukhim, Rameen, Salvesen, Helga B., Cherniack, Andrew D.
Publicado no Sci Rep (2016)

Corrigendum: Recurrent hormone-binding domain truncated ESR1 amplifications in primary endometrial cancers suggest their implication in hormone independent growth

Por Holst, Frederik, Hoivik, Erling A., Gibson, William J., Taylor-Weiner, Amaro, Schumacher, Steven E., Asmann, Yan W., Grossmann, Patrick, Trovik, Jone, Necela, Brian M., Thompson, E. Aubrey, Meyerson, Matthew, Beroukhim, Rameen, Salvesen, Helga B., Cherniack, Andrew D.
Publicado no Sci Rep (2016)

Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background

Por Elvers, Ingegerd, Turner-Maier, Jason, Swofford, Ross, Koltookian, Michele, Johnson, Jeremy, Stewart, Chip, Zhang, Cheng-Zhong, Schumacher, Steven E., Beroukhim, Rameen, Rosenberg, Mara, Thomas, Rachael, Mauceli, Evan, Getz, Gad, Palma, Federica Di, Modiano, Jaime F., Breen, Matthew, Lindblad-Toh, Kerstin, Alföldi, Jessica
Publicado no Genome Res (2015)

Pan-cancer patterns of somatic copy-number alteration

Por Zack, Travis I., Schumacher, Steven E., Carter, Scott L., Cherniack, Andrew D., Saksena, Gordon, Tabak, Barbara, Lawrence, Michael S., Zhang, Cheng-Zhong, Wala, Jeremiah, Mermel, Craig H., Sougnez, Carrie, Gabriel, Stacey B., Hernandez, Bryan, Shen, Hui, Laird, Peter W., Getz, Gad, Meyerson, Matthew, Beroukhim, Rameen
Publicado em 2013

Cancer vulnerabilities unveiled by genomic loss

Por Nijhawan, Deepak, Zack, Travis I., Ren, Yin, Strickland, Matthew R., Lamothe, Rebecca, Schumacher, Steven E., Tsherniak, Aviad, Besche, Henrike C., Rosenbluh, Joseph, Shehata, Shyemaa, Cowley, Glenn S., Weir, Barbara A., Goldberg, Alfred L., Mesirov, Jill P., Root, David E., Bhatia, Sangeeta N., Beroukhim, Rameen, Hahn, William C.
Publicado em 2012

Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy

Por Lohr, Jens G., Stojanov, Petar, Carter, Scott L., Cruz-Gordillo, Peter, Lawrence, Michael S., Auclair, Daniel, Sougnez, Carrie, Knoechel, Birgit, Gould, Joshua, Saksena, Gordon, Cibulskis, Kristian, McKenna, Aaron, Chapman, Michael A., Straussman, Ravid, Levy, Joan, Perkins, Louise M., Keats, Jonathan J., Schumacher, Steven E., Rosenberg, Mara, Getz, Gad, Golub, Todd R.
Publicado no Cancer Cell (2014)

β-catenin driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis

Por Rosenbluh, Joseph, Nijhawan, Deepak, Cox, Andrew G., Li, Xingnan, Neal, James T., Schafer, Eric J., Zack, Travis I., Wang, Xiaoxing, Tsherniak, Aviad, Schinzel, Anna C., Shao, Diane D., Schumacher, Steven E., Weir, Barbara A., Vazquez, Francisca, Cowley, Glenn S., Root, David E., Mesirov, Jill P., Beroukhim, Rameen, Kuo, Calvin J., Goessling, Wolfram, Hahn, William C.
Publicado em 2012

Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers

Por Hagerstrand, Daniel, Tong, Alexander, Schumacher, Steven E., Ilic, Nina, Shen, Rhine R., Cheung, Hiu Wing, Vazquez, Francisca, Shrestha, Yashaswi, Kim, So Young, Giacomelli, Andrew O., Rosenbluh, Joseph, Schinzel, Anna C., Spardy, Nicole A., Barbie, David A., Mermel, Craig H., Weir, Barbara A., Garraway, Levi A., Tamayo, Pablo, Mesirov, Jill P., Beroukhim, Rameen, Hahn, William C.
Publicado em 2013

BET-bromodomain inhibition of MYC-amplified medulloblastoma

Por Bandopadhayay, Pratiti, Bergthold, Guillaume, Nguyen, Brian, Schubert, Simone, Gholamin, Sharareh, Tang, Yujie, Bolin, Sara, Schumacher, Steven E, Zeid, Rhamy, Masoud, Sabran, Yu, Furong, Vue, Nujsaubnusi, Gibson, William J, Paolella, Brenton R, Mitra, Siddharta, Cheshier, Samuel, Qi, Jun, Liu, Kun-Wei, Wechsler-Reya, Robert, Weiss, William A, Swartling, Fredrik J, Kieran, Mark W, Bradner, James E, Beroukhim, Rameen, Cho, Yoon-Jae
Publicado em 2013

Expression profiles of 151 pediatric low-grade gliomas reveal molecular differences associated with location and histological subtype

Por Bergthold, Guillaume, Bandopadhayay, Pratiti, Hoshida, Yujin, Ramkissoon, Shakti, Ramkissoon, Lori, Rich, Benjamin, Maire, Cecile L., Paolella, Brenton R., Schumacher, Steven E., Tabak, Barbara, Ferrer-Luna, Ruben, Ozek, Memet, Sav, Aydin, Santagata, Sandro, Wen, Patrick Yung, Goumnerova, Liliana C., Ligon, Azra H., Stiles, Charles, Segal, Rosalind, Golub, Todd, Grill, Jacques, Ligon, Keith L., Chan, Jennifer A., Kieran, Mark W., Beroukhim, Rameen
Publicado no Neuro Oncol (2015)

Exome and whole genome sequencing of esophageal adenocarcinoma identifies recurrent driver events and mutational complexity

Por Dulak, Austin M., Stojanov, Petar, Peng, Shouyong, Lawrence, Michael S., Fox, Cameron, Stewart, Chip, Bandla, Santhoshi, Imamura, Yu, Schumacher, Steven E., Shefler, Erica, McKenna, Aaron, Cibulskis, Kristian, Sivachenko, Andrey, Carter, Scott L., Saksena, Gordon, Voet, Douglas, Ramos, Alex H., Auclair, Daniel, Thompson, Kristin, Sougnez, Carrie, Onofrio, Robert C., Guiducci, Candace, Beroukhim, Rameen, Zhou, David, Lin, Lin, Lin, Jules, Reddy, Rishindra, Chang, Andrew, Luketich, James D., Pennathur, Arjun, Ogino, Shuji, Golub, Todd R., Gabriel, Stacey B., Lander, Eric S., Beer, David G., Godfrey, Tony E., Getz, Gad, Bass, Adam J.
Publicado em 2013

Genomic analysis of diffuse pediatric low-grade gliomas identifies recurrent oncogenic truncating rearrangements in the transcription factor MYBL1

Por Ramkissoon, Lori A., Horowitz, Peleg M., Craig, Justin M., Ramkissoon, Shakti H., Rich, Benjamin E., Schumacher, Steven E., McKenna, Aaron, Lawrence, Michael S., Bergthold, Guillaume, Brastianos, Priscilla K., Tabak, Barbara, Ducar, Matthew D., Van Hummelen, Paul, MacConaill, Laura E., Pouissant-Young, Tina, Cho, Yoon-Jae, Taha, Hala, Mahmoud, Madeha, Bowers, Daniel C., Margraf, Linda, Tabori, Uri, Hawkins, Cynthia, Packer, Roger J., Hill, D. Ashley, Pomeroy, Scott L., Eberhart, Charles G., Dunn, Ian F., Goumnerova, Liliana, Getz, Gad, Chan, Jennifer A., Santagata, Sandro, Hahn, William C., Stiles, Charles D., Ligon, Azra H., Kieran, Mark W., Beroukhim, Rameen, Ligon, Keith L.
Publicado em 2013