Targeting MYCN in Neuroblastoma by BET Bromodomain Inhibition

Por Puissant, Alexandre, Frumm, Stacey M., Alexe, Gabriela, Bassil, Christopher F., Qi, Jun, Chanthery, Yvan H., Nekritz, Erin A., Zeid, Rhamy, Gustafson, W. Clay, Greninger, Patricia, Garnett, Matthew J., McDermott, Ultan, Benes, Cyril H., Kung, Andrew L., Weiss, William A., Bradner, James E., Stegmaier, Kimberly
Publicado em 2013

Pro-invasion metastasis drivers in early stage melanoma are oncogenes

Por Scott, Kenneth L., Nogueira, Cristina, Heffernan, Timothy P., van Doorn, Remco, Dhakal, Sabin, Hanna, Jason A., Min, Chengyin, Jaskelioff, Mariela, Xiao, Yonghong, Wu, Chang-Jiun, Cameron, Lisa A., Perry, Samuel R., Zeid, Rhamy, Feinberg, Tamar, Kim, Minjung, Woude, George Vande, Granter, Scott R., Bosenberg, Marcus, Chu, Gerald C., DePinho, Ronald A., Rimm, David L., Chin, Lynda
Publicado em 2011

BET-bromodomain inhibition of MYC-amplified medulloblastoma

Por Bandopadhayay, Pratiti, Bergthold, Guillaume, Nguyen, Brian, Schubert, Simone, Gholamin, Sharareh, Tang, Yujie, Bolin, Sara, Schumacher, Steven E, Zeid, Rhamy, Masoud, Sabran, Yu, Furong, Vue, Nujsaubnusi, Gibson, William J, Paolella, Brenton R, Mitra, Siddharta, Cheshier, Samuel, Qi, Jun, Liu, Kun-Wei, Wechsler-Reya, Robert, Weiss, William A, Swartling, Fredrik J, Kieran, Mark W, Bradner, James E, Beroukhim, Rameen, Cho, Yoon-Jae
Publicado em 2013

Active medulloblastoma enhancers reveal subgroup-specific cellular origins

Por Lin, Charles Y., Erkek, Serap, Tong, Yiai, Yin, Linlin, Federation, Alexander J., Zapatka, Marc, Haldipur, Parthiv, Kawauchi, Daisuke, Risch, Thomas, Warnatz, Hans-Jörg, Worst, Barbara C., Ju, Bensheng, Orr, Brent A., Zeid, Rhamy, Polaski, Donald R., Segura-Wang, Maia, Waszak, Sebastian M., Jones, David T.W., Kool, Marcel, Hovestadt, Volker, Buchhalter, Ivo, Sieber, Laura, Johann, Pascal, Chavez, Lukas, Gröschel, Stefan, Ryzhova, Marina, Korshunov, Andrey, Chen, Wenbiao, Chizhikov, Victor V., Millen, Kathleen J., Amstislavskiy, Vyacheslav, Lehrach, Hans, Yaspo, Marie-Laure, Eils, Roland, Lichter, Peter, Korbel, Jan O., Pfister, Stefan M., Bradner, James E., Northcott, Paul A.
Publicado no Nature (2016)

Melanoma genome sequencing reveals frequent PREX2 mutations

Por Berger, Michael F., Hodis, Eran, Heffernan, Timothy P., Deribe, Yonathan Lissanu, Lawrence, Michael S., Protopopov, Alexei, Ivanova, Elena, Watson, Ian R., Nickerson, Elizabeth, Ghosh, Papia, Zhang, Hailei, Zeid, Rhamy, Ren, Xiaojia, Cibulskis, Kristian, Sivachenko, Andrey Y., Wagle, Nikhil, Sucker, Antje, Sougnez, Carrie, Onofrio, Robert, Ambrogio, Lauren, Auclair, Daniel, Fennell, Timothy, Carter, Scott L., Drier, Yotam, Stojanov, Petar, Singer, Meredith A., Voet, Douglas, Jing, Rui, Saksena, Gordon, Barretina, Jordi, Ramos, Alex H., Pugh, Trevor J., Stransky, Nicolas, Parkin, Melissa, Winckler, Wendy, Mahan, Scott, Ardlie, Kristin, Baldwin, Jennifer, Wargo, Jennifer, Schadendorf, Dirk, Meyerson, Matthew, Gabriel, Stacey B., Golub, Todd R., Wagner, Stephan N., Lander, Eric S., Getz, Gad, Chin, Lynda, Garraway, Levi A.
Publicado em 2012

MYB-QKI rearrangements in Angiocentric Glioma drive tumorigenicity through a tripartite mechanism

Por Bandopadhayay, Pratiti, Ramkissoon, Lori A., Jain, Payal, Bergthold, Guillaume, Wala, Jeremiah, Zeid, Rhamy, Schumacher, Steven E., Urbanski, Laura, O’Rourke, Ryan, Gibson, William J., Pelton, Kristine, Ramkissoon, Shakti H., Han, Harry J., Zhu, Yuankun, Choudhari, Namrata, Silva, Amanda, Boucher, Katie, Henn, Rosemary E., Kang, Yun Jee, Knoff, David, Paolella, Brenton R., Gladden-Young, Adrianne, Varlet, Pascale, Pages, Melanie, Horowitz, Peleg M., Federation, Alexander, Malkin, Hayley, Tracy, Adam, Seepo, Sara, Ducar, Matthew, Hummelen, Paul Van, Santi, Mariarita, Buccoliero, Anna Maria, Scagnet, Mirko, Bowers, Daniel C., Giannini, Caterina, Puget, Stephanie, Hawkins, Cynthia, Tabori, Uri, Klekner, Almos, Bognar, Laszlo, Burger, Peter C., Eberhart, Charles, Rodriguez, Fausto J., Hill, D. Ashley, Mueller, Sabine, Haas-Kogan, Daphne A., Phillips, Joanna J., Santagata, Sandro, Stiles, Charles D., Bradner, James E., Jabado, Nada, Goren, Alon, Grill, Jacques, Ligon, Azra H., Goumnerova, Liliana, Waanders, Angela J., Storm, Phillip B., Kieran, Mark W., Ligon, Keith L., Beroukhim, Rameen, Resnick, Adam C.
Publicado no Nat Genet (2016)