An accessible GenePattern notebook for the copy number variation analysis of Illumina Infinium DNA methylation arrays

par Mah, Clarence K., Mesirov, Jill P., Chavez, Lukas
Publié dans F1000Res (2018)

MEDIPS: genome-wide differential coverage analysis of sequencing data derived from DNA enrichment experiments

par Lienhard, Matthias, Grimm, Christina, Morkel, Markus, Herwig, Ralf, Chavez, Lukas
Publié 2014

In silico identification of a core regulatory network of OCT4 in human embryonic stem cells using an integrated approach

par Chavez, Lukas, Bais, Abha S, Vingron, Martin, Lehrach, Hans, Adjaye, James, Herwig, Ralf
Publié 2009

Dynamic EBF1 occupancy directs sequential epigenetic and transcriptional events in B-cell programming

par Li, Rui, Cauchy, Pierre, Ramamoorthy, Senthilkumar, Boller, Sören, Chavez, Lukas, Grosschedl, Rudolf
Publié dans Genes Dev (2018)

InTAD: chromosome conformation guided analysis of enhancer target genes

par Okonechnikov, Konstantin, Erkek, Serap, Korbel, Jan O., Pfister, Stefan M., Chavez, Lukas
Publié dans BMC Bioinformatics (2019)

A Data Integration Approach to Mapping OCT4 Gene Regulatory Networks Operative in Embryonic Stem Cells and Embryonal Carcinoma Cells

par Jung, Marc, Peterson, Hedi, Chavez, Lukas, Kahlem, Pascal, Lehrach, Hans, Vilo, Jaak, Adjaye, James
Publié 2010

A probabilistic generative model for quantification of DNA modifications enables analysis of demethylation pathways

par Äijö, Tarmo, Huang, Yun, Mannerström, Henrik, Chavez, Lukas, Tsagaratou, Ageliki, Rao, Anjana, Lähdesmäki, Harri
Publié dans Genome Biol (2016)

EPND-01. THE ACTIVE REGULATORY LANDSCAPE OF EPENDYMAL TUMORS

par Mack, Stephen, Pajtler, Kristian, Chavez, Lukas, Pfister, Stefan, Kool, Marcel, Taylor, Michael, Rich, Jeremy
Publié dans Neuro Oncol (2017)

Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage

par Chavez, Lukas, Jozefczuk, Justyna, Grimm, Christina, Dietrich, Jörn, Timmermann, Bernd, Lehrach, Hans, Herwig, Ralf, Adjaye, James
Publié 2010

Predicting Cell Types and Genetic Variations Contributing to Disease by Combining GWAS and Epigenetic Data

par Gerasimova, Anna, Chavez, Lukas, Li, Bin, Seumois, Gregory, Greenbaum, Jason, Rao, Anjana, Vijayanand, Pandurangan, Peters, Bjoern
Publié 2013

PDTM-23. THE ACTIVE REGULATORY LANDSCAPE OF EPENDYMAL TUMORS

par Mack, Stephen, Pajtler, Kristian W, Chavez, Lukas, Pfister, Stefan M, Kool, Marcel, Taylor, Michael, Rich, Jeremy
Publié dans Neuro Oncol (2017)

PNR-12 GENOME-WIDE PROFILING OF EMBRYONAL TUMORS WITH MULTILAYERED ROSETTES (ETMR)

par Lambo, Sander, Bunt, Jens, Schmidt, Christine, Pfister, Stefan M., Richards, Linda J., Chavez, Lukas, Korshunov, Andrey, Kool, Marcel
Publié dans Neuro Oncol (2016)

Tet proteins influence the balance between neuroectodermal and mesodermal fate choice by inhibiting Wnt signaling

par Li, Xiang, Yue, Xiaojing, Pastor, William A., Lin, Lizhu, Georges, Romain, Chavez, Lukas, Evans, Sylvia M., Rao, Anjana
Publié dans Proc Natl Acad Sci U S A (2016)

Combinatorial Binding in Human and Mouse Embryonic Stem Cells Identifies Conserved Enhancers Active in Early Embryonic Development

par Göke, Jonathan, Jung, Marc, Behrens, Sarah, Chavez, Lukas, O'Keeffe, Sean, Timmermann, Bernd, Lehrach, Hans, Adjaye, James, Vingron, Martin
Publié 2011

Innate-like functions of natural killer T cell subsets result from highly divergent gene programs

par Engel, Isaac, Seumois, Grégory, Chavez, Lukas, Samaniego-Castruita, Daniela, White, Brandie, Chawla, Ashu, Mock, Dennis, Vijayanand, Pandurangan, Kronenberg, Mitchell
Publié dans Nat Immunol (2016)

Dynamic changes in chromatin accessibility in CD8(+) T cells responding to viral infection

par Scott-Browne, James P., López-Moyado, Isaac F., Trifari, Sara, Wong, Victor, Chavez, Lukas, Rao, Anjana, Pereira, Renata M.
Publié dans Immunity (2016)

17q21 asthma-risk variants switch CTCF binding and regulate IL-2 production by T cells

par Schmiedel, Benjamin Joachim, Seumois, Grégory, Samaniego-Castruita, Daniela, Cayford, Justin, Schulten, Veronique, Chavez, Lukas, Ay, Ferhat, Sette, Alessandro, Peters, Bjoern, Vijayanand, Pandurangan
Publié dans Nat Commun (2016)

ATRT-09. CHROMATIN SEGMENTATION ANALYSES IN ATYPICAL TERATOID/RHABDOID TUMORS REVEAL H3K27ME3-MEDIATED EPIGENETIC SILENCING OF TUMOR SUPPRESSOR GENES AND IDENTIFY A NOVEL ROLE OF E...

par Johann, Pascal D., Erkek, Serap, Chavez, Lukas, Finetti, Martina, Kerl, Kornelius, Zapatka, Marc, Gajjar, Amar, Hasselblatt, Martin, Pfister, Stefan M., Kool, Marcel
Publié dans Neuro Oncol (2017)

MBCL-42. SECOND GENERATION MOLECULAR SUBGROUPING OF MEDULLOBLASTOMA: TOWARDS A WORKING CONSENSUS OF GROUP 3/4 SUBTYPES

par Sharma, Tanvi, Schwalbe, Edward C, Williamson, Daniel, Hovestadt, Volker, Chavez, Lukas, Kool, Marcel, Northcott, Paul A, Pfister, Stefan M, Clifford, Steven C
Publié dans Neuro Oncol (2018)

Acute loss of TET function results in aggressive myeloid cancer in mice

par An, Jungeun, González-Avalos, Edahí, Chawla, Ashu, Jeong, Mira, López-Moyado, Isaac F., Li, Wei, Goodell, Margaret A., Chavez, Lukas, Ko, Myunggon, Rao, Anjana
Publié dans Nat Commun (2015)