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Dynamic changes in chromatin accessibility in CD8(+) T cells responding to viral infection

In response to acute infection, naive CD8(+) T cells expand, differentiate into effector cells and then contract to a long-lived pool of memory cells after pathogen clearance. During chronic infections or in tumors, CD8(+) T cells acquire an “exhausted” phenotype. Here we present genome-wide compari...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Scott-Browne, James P., López-Moyado, Isaac F., Trifari, Sara, Wong, Victor, Chavez, Lukas, Rao, Anjana, Pereira, Renata M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5214519/
https://ncbi.nlm.nih.gov/pubmed/27939672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2016.10.028
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