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Exhaustion-associated regulatory regions in CD8(+) tumor-infiltrating T cells
T-cell exhaustion is a progressive loss of effector function and memory potential due to persistent antigen exposure, which occurs in chronic viral infections and cancer. Here we investigate the relation between gene expression and chromatin accessibility in CD8(+) tumor-infiltrating lymphocytes (TI...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5380094/ https://ncbi.nlm.nih.gov/pubmed/28283662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620498114 |
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