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Transcriptional regulatory network for the establishment of CD8(+) T cell exhaustion

Chronic infection with persistent antigenic stimulation results in the generation of exhausted CD8(+) T cells, which are considered defective effector CD8(+) T cells, and thus compromises effective immune responses. However, recent studies have illustrated that exhausted CD8(+) T cells may be purpos...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Seo, Wooseok, Jerin, Chandsultana, Nishikawa, Hiroyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8080584/
https://ncbi.nlm.nih.gov/pubmed/33627794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s12276-021-00568-0
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