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Predicting Cell Types and Genetic Variations Contributing to Disease by Combining GWAS and Epigenetic Data

Genome-wide association studies (GWASs) identify single nucleotide polymorphisms (SNPs) that are enriched in individuals suffering from a given disease. Most disease-associated SNPs fall into non-coding regions, so that it is not straightforward to infer phenotype or function; moreover, many SNPs ar...

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Detalhes bibliográficos
Main Authors: Gerasimova, Anna, Chavez, Lukas, Li, Bin, Seumois, Gregory, Greenbaum, Jason, Rao, Anjana, Vijayanand, Pandurangan, Peters, Bjoern
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3559682/
https://ncbi.nlm.nih.gov/pubmed/23382893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054359
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