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Predicting Cell Types and Genetic Variations Contributing to Disease by Combining GWAS and Epigenetic Data
Genome-wide association studies (GWASs) identify single nucleotide polymorphisms (SNPs) that are enriched in individuals suffering from a given disease. Most disease-associated SNPs fall into non-coding regions, so that it is not straightforward to infer phenotype or function; moreover, many SNPs ar...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3559682/ https://ncbi.nlm.nih.gov/pubmed/23382893 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0054359 |
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