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Transcriptional profile of TB antigen-specific T cells reveals novel multifunctional features

In latent tuberculosis infection (LTBI) spread of the bacteria is contained by a persistent immune response, which includes CD4(+) T cells as important contributors. Here we show that TB-specific CD4(+) T cells have a characteristic chemokine expression signature (CCR6(+)CXCR3(+)CCR4(−)), and that t...

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Detalhes bibliográficos
Main Authors: Arlehamn, Cecilia Lindestam, Seumois, Gregory, Gerasimova, Anna, Huang, Charlie, Fu, Zheng, Yue, Xiaojing, Sette, Alessandro, Vijayanand, Pandurangan, Peters, Bjoern
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4157075/
https://ncbi.nlm.nih.gov/pubmed/25092889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401151
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