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Computational analysis of genome-wide DNA methylation during the differentiation of human embryonic stem cells along the endodermal lineage

The generation of genome-wide data derived from methylated DNA immunoprecipitation followed by sequencing (MeDIP-seq) has become a major tool for epigenetic studies in health and disease. The computational analysis of such data, however, still falls short on accuracy, sensitivity, and speed. We prop...

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Autors principals: Chavez, Lukas, Jozefczuk, Justyna, Grimm, Christina, Dietrich, Jörn, Timmermann, Bernd, Lehrach, Hans, Herwig, Ralf, Adjaye, James
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945193/
https://ncbi.nlm.nih.gov/pubmed/20802089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.110114.110
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