MBRS-19. BIOCHEMICAL AND ONCOGENIC CHARACTERIZATION OF HOTSPOT KBTBD4 MUTATIONS IN MEDULLOBLASTOMA

door Muniz-Talavera, Hilmarie, Hadley, Jennifer, Northcott, Paul A
Gepubliceerd in Neuro Oncol (2018)

Medulloblastoma genomics in the modern molecular era

door Kumar, Rahul, Liu, Anthony P. Y., Northcott, Paul A.
Gepubliceerd in Brain Pathol (2019)

Mouse models of medulloblastoma

door Wu, Xiaochong, Northcott, Paul A., Croul, Sidney, Taylor, Michael D.
Gepubliceerd in 2011

Molecular subgroups of medulloblastoma

door Northcott, Paul A, Dubuc, Adrian M, Pfister, Stefan, Taylor, Michael D
Gepubliceerd in Expert Rev Neurother (2012)

The Role of Chromatin Remodeling in Medulloblastoma

door Jones, David T. W., Northcott, Paul A., Kool, Marcel, Pfister, Stefan M.
Gepubliceerd in Brain Pathol (2013)

Advances in classification of pediatric brain tumors through DNA methylation profiling: from research tool to frontline diagnostic

door Kumar, Rahul, Liu, Anthony P.Y., Orr, Brent A., Northcott, Paul A., Robinson, Giles W.
Gepubliceerd in Cancer (2018)

Depletion of kinesin motor KIF20A to target cell fate control suppresses medulloblastoma tumour growth

door Qiu, Runxiang, Wu, Jun, Gudenas, Brian, Northcott, Paul A., Wechsler-Reya, Robert J., Lu, Qiang
Gepubliceerd in Commun Biol (2021)

MOLECULAR (RE-)CLASSIFICATION OF CNS-PRIMITIVE NEUROECTODERMAL TUMORS

door Kool, Marcel, Sturm, Dominik, Northcott, Paul A., Jones, David T.W., Korshunov, Andrey, Lichter, Peter, Pfister, Stefan
Gepubliceerd in 2014

TMOD-01 BCOR IS A NOVEL TUMOR SUPPRESSOR GENE IN SHH-DRIVEN MEDULLOBLASTOMA

door Batora, Nadja V., Giese, Marcus, Sieber, Laura, Pfister, Stefan M., Bardwell, Vivian, Kawauchi, Daisuke, Northcott, Paul A.
Gepubliceerd in Neuro Oncol (2015)

STRUCTURAL VARIANTS SHUFFLE CHROMATIN TO ACTIVATE GFI1 FAMILY ONCOGENES IN MEDULLOBLASTOMA

door Northcott, Paul A., Lee, Catherine, Zichner, Thomas, Lichter, Peter, Korbel, Jan O., Wechsler-Reya, Robert J., Pfister, Stefan M.
Gepubliceerd in 2014

PM-09 REGULATION OF MEDULLOBLASTOMA FORMATION BY Gfi1 AND Gfi1B

door Lee, Catherine, Northcott, Paul A., Zichner, Thomas, Lichter, Peter, Korbel, Jan O., Pfister, Stefan M., Wechsler-Reya, Robert J.
Gepubliceerd in 2014

YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation

door Fernandez-L, Africa, Northcott, Paul A., Dalton, James, Fraga, Charles, Ellison, David, Angers, Stephane, Taylor, Michael D., Kenney, Anna Marie
Gepubliceerd in 2009

Functional Genomics Identifies Drivers of Medulloblastoma Dissemination

door Mumert, Michael, Dubuc, Adrian, Wu, Xiaochong, Northcott, Paul A., Chin, Steven S., Pedone, Carolyn A., Taylor, Michael D., Fults, Daniel W.
Gepubliceerd in 2012

Targeting the Enhancer of Zeste Homologue 2 in Medulloblastoma

door Alimova, Irina, Venkataraman, Sujatha, Harris, Peter, Marquez, Victor E., Northcott, Paul A, Dubuc, Adrian, Taylor, Michael D, Foreman, Nicholas K, Vibhakar, Rajeev
Gepubliceerd in 2012

Deep Sequencing Identifies IDH1 R132S Mutation in Adult Medulloblastoma

door Snuderl, Matija, Triscott, Joanna, Northcott, Paul A., Shih, Helen A., Kong, Esther, Robinson, Hayley, Dunn, Sandra E., Iafrate, A. John, Yip, Stephen
Gepubliceerd in J Clin Oncol (2015)

MBCL-42. SECOND GENERATION MOLECULAR SUBGROUPING OF MEDULLOBLASTOMA: TOWARDS A WORKING CONSENSUS OF GROUP 3/4 SUBTYPES

door Sharma, Tanvi, Schwalbe, Edward C, Williamson, Daniel, Hovestadt, Volker, Chavez, Lukas, Kool, Marcel, Northcott, Paul A, Pfister, Stefan M, Clifford, Steven C
Gepubliceerd in Neuro Oncol (2018)

Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mTOR activity and p27(Kip1) localization

door Bhatia, Bobby, Northcott, Paul A., Hambardzumyan, Dolores, Govindarajan, Baskaran, Brat, Daniel J., Arbiser, Jack L., Holland, Eric C., Taylor, Michael D., Kenney, Anna Marie
Gepubliceerd in 2009

The WIP1 Oncogene Promotes Progression and Invasion of Aggressive Medulloblastoma Variants

door Buss, Meghan C., Remke, Marc, Lee, Juhyun, Gandhi, Khanjan, Schniederjan, Matthew J., Kool, Marcel, Northcott, Paul A., Pfister, Stefan M., Taylor, Michael D., Castellino, Robert C.
Gepubliceerd in Oncogene (2014)

Bridging the treatment gap in infant medulloblastoma: molecularly informed outcomes of a globally feasible regimen

door Baroni, Lorena V, Sampor, Claudia, Gonzalez, Adriana, Lubieniecki, Fabiana, Lamas, Gabriela, Rugilo, Carlos, Bartels, Ute, Heled, Ayala, Smith, Kyle S, Northcott, Paul A, Bouffet, Eric, Alderete, Daniel, Ramaswamy, Vijay
Gepubliceerd in Neuro Oncol (2020)

OTX2 is critical for the maintenance and progression of classic medulloblastoma

door Adamson, David C., Shi, Qun, Wortham, Matthew, Northcott, Paul A., Di, Chunhui, Duncan, Christopher G., Li, Jianjun, McLendon, Roger E., Bigner, Darell D., Taylor, Michael D., Yan, Hai
Gepubliceerd in 2009