Mouse models of medulloblastoma

Por Wu, Xiaochong, Northcott, Paul A., Croul, Sidney, Taylor, Michael D.
Publicado em 2011

Molecular subgroups of medulloblastoma

Por Northcott, Paul A, Dubuc, Adrian M, Pfister, Stefan, Taylor, Michael D
Publicado no Expert Rev Neurother (2012)

MOLECULAR (RE-)CLASSIFICATION OF CNS-PRIMITIVE NEUROECTODERMAL TUMORS

Por Kool, Marcel, Sturm, Dominik, Northcott, Paul A., Jones, David T.W., Korshunov, Andrey, Lichter, Peter, Pfister, Stefan
Publicado em 2014

TMOD-01 BCOR IS A NOVEL TUMOR SUPPRESSOR GENE IN SHH-DRIVEN MEDULLOBLASTOMA

Por Batora, Nadja V., Giese, Marcus, Sieber, Laura, Pfister, Stefan M., Bardwell, Vivian, Kawauchi, Daisuke, Northcott, Paul A.
Publicado no Neuro Oncol (2015)

STRUCTURAL VARIANTS SHUFFLE CHROMATIN TO ACTIVATE GFI1 FAMILY ONCOGENES IN MEDULLOBLASTOMA

Por Northcott, Paul A., Lee, Catherine, Zichner, Thomas, Lichter, Peter, Korbel, Jan O., Wechsler-Reya, Robert J., Pfister, Stefan M.
Publicado em 2014

PM-09 REGULATION OF MEDULLOBLASTOMA FORMATION BY Gfi1 AND Gfi1B

Por Lee, Catherine, Northcott, Paul A., Zichner, Thomas, Lichter, Peter, Korbel, Jan O., Pfister, Stefan M., Wechsler-Reya, Robert J.
Publicado em 2014

YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation

Por Fernandez-L, Africa, Northcott, Paul A., Dalton, James, Fraga, Charles, Ellison, David, Angers, Stephane, Taylor, Michael D., Kenney, Anna Marie
Publicado em 2009

Functional Genomics Identifies Drivers of Medulloblastoma Dissemination

Por Mumert, Michael, Dubuc, Adrian, Wu, Xiaochong, Northcott, Paul A., Chin, Steven S., Pedone, Carolyn A., Taylor, Michael D., Fults, Daniel W.
Publicado em 2012

Targeting the Enhancer of Zeste Homologue 2 in Medulloblastoma

Por Alimova, Irina, Venkataraman, Sujatha, Harris, Peter, Marquez, Victor E., Northcott, Paul A, Dubuc, Adrian, Taylor, Michael D, Foreman, Nicholas K, Vibhakar, Rajeev
Publicado em 2012

Deep Sequencing Identifies IDH1 R132S Mutation in Adult Medulloblastoma

Por Snuderl, Matija, Triscott, Joanna, Northcott, Paul A., Shih, Helen A., Kong, Esther, Robinson, Hayley, Dunn, Sandra E., Iafrate, A. John, Yip, Stephen
Publicado no J Clin Oncol (2015)

Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mTOR activity and p27(Kip1) localization

Por Bhatia, Bobby, Northcott, Paul A., Hambardzumyan, Dolores, Govindarajan, Baskaran, Brat, Daniel J., Arbiser, Jack L., Holland, Eric C., Taylor, Michael D., Kenney, Anna Marie
Publicado em 2009

The WIP1 Oncogene Promotes Progression and Invasion of Aggressive Medulloblastoma Variants

Por Buss, Meghan C., Remke, Marc, Lee, Juhyun, Gandhi, Khanjan, Schniederjan, Matthew J., Kool, Marcel, Northcott, Paul A., Pfister, Stefan M., Taylor, Michael D., Castellino, Robert C.
Publicado no Oncogene (2014)

OTX2 is critical for the maintenance and progression of classic medulloblastoma

Por Adamson, David C., Shi, Qun, Wortham, Matthew, Northcott, Paul A., Di, Chunhui, Duncan, Christopher G., Li, Jianjun, McLendon, Roger E., Bigner, Darell D., Taylor, Michael D., Yan, Hai
Publicado em 2009

Medulloblastomics: The End of the Beginning

Por Northcott, Paul A, Jones, David TW, Kool, Marcel, Robinson, Giles W, Gilbertson, Richard J, Cho, Yoon-Jae, Pomeroy, Scott L, Korshunov, Andrey, Lichter, Peter, Taylor, Michael D, Pfister, Stefan M
Publicado em 2012

GE-07 DNA METHYLATION IN MEDULLOBLASTOMA AND MOLECULAR DIAGNOSTICS OF BRAIN TUMORS

Por Hovestadt, Volker, Capper, David, Sill, Martin, Picelli, Simone, Wang, Wei, Northcott, Paul A., Kool, Marcel, Zapatka, Marc, Radlwimmer, Bernhard, von Deimling, Andreas, Pfister, Stefan M., Lichter, Peter, Jones, David T. W.
Publicado no Neuro Oncol (2015)

MyoD is a tumor suppressor gene in Medulloblastoma

Por Dey, Joyoti, Dubuc, Adrian M., Pedro, Kyle D., Thirstrup, Derek, Mecham, Brig, Northcott, Paul A., Wu, Xiaochong, Shih, David, Tapscott, Stephen J., LeBlanc, Michael, Taylor, Michael D., Olson, James M.
Publicado em 2013

Medulloblastoma Comprises Four Distinct Molecular Variants

Por Northcott, Paul A., Korshunov, Andrey, Witt, Hendrik, Hielscher, Thomas, Eberhart, Charles G., Mack, Stephen, Bouffet, Eric, Clifford, Steven C., Hawkins, Cynthia E., French, Pim, Rutka, James T., Pfister, Stefan, Taylor, Michael D.
Publicado no J Clin Oncol (2011)

The miR-17/92 polycistron is up-regulated in Sonic hedgehog-driven medulloblastomas and induced by N-myc in Sonic hedgehog-treated cerebellar neural precursors

Por Northcott, Paul A., Fernandez-L, Africa, Hagan, John P., Ellison, David W., Grajkowska, Wesia, Gillespie, Yancey, Grundy, Richard, Van Meter, Timothy, Rutka, James T., Croce, Carlo M., Kenney, Anna Marie, Taylor, Michael D.
Publicado em 2009

EPIG-04 THE CHROMATIN LANDSCAPE OF MEDULLOBLASTOMA

Por Erkek, Serap, Zapatka, Marc, Chavez, Lukas, Waszak, Sebastian M., Hovestadt, Volker, Johann, Pascal D., Sieber, Laura, Jones, David T. W., Kool, Marcel, Lichter, Peter, Korbel, Jan O., Northcott, Paul A., Pfister, Stefan M.
Publicado no Neuro Oncol (2015)

Distinct Neural Stem Cell Populations Give Rise to Disparate Brain Tumors in Response to N-MYC

Por Swartling, Fredrik J., Savov, Vasil, Persson, Anders I., Chen, Justin, Hackett, Christopher S., Northcott, Paul A., Grimmer, Matthew R., Lau, Jasmine, Chesler, Louis, Perry, Arie, Phillips, Joanna J., Taylor, Michael D., Weiss, William A.
Publicado em 2012