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MOLECULAR (RE-)CLASSIFICATION OF CNS-PRIMITIVE NEUROECTODERMAL TUMORS

BACKGROUND: According to the current WHO classification of CNS tumors, childhood CNS primitive neuro-ectodermal tumors (CNS-PNETs; WHO °IV) are poorly differentiated embryonal tumors with early onset and aggressive clinical behavior. Histological diagnosis can be complicated by morphological heterog...

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Detalhes bibliográficos
Main Authors: Kool, Marcel, Sturm, Dominik, Northcott, Paul A., Jones, David T.W., Korshunov, Andrey, Lichter, Peter, Pfister, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144575/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou208.3
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