YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation

Medulloblastoma is the most common solid malignancy of childhood, with treatment side effects reducing survivors’ quality of life and lethality being associated with tumor recurrence. Activation of the Sonic hedgehog (Shh) signaling pathway is implicated in human medulloblastomas. Cerebellar granule...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Fernandez-L, Africa, Northcott, Paul A., Dalton, James, Fraga, Charles, Ellison, David, Angers, Stephane, Taylor, Michael D., Kenney, Anna Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2009
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2788333/
https://ncbi.nlm.nih.gov/pubmed/19952108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1824509
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados