Upregulation of the chromatin remodeler HELLS is mediated by YAP1 in Sonic Hedgehog Medulloblastoma

Medulloblastoma is a malignant pediatric tumor that arises from neural progenitors in the cerebellum. Despite a five-year survival rate of ~70%, nearly all patients incur adverse side effects from current treatment strategies that drastically impact quality of life. Roughly one-third of medulloblast...

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Vydáno v:Sci Rep
Hlavní autoři: Robinson, M. Hope, Maximov, Victor, Lallani, Shoeb, Farooq, Hamza, Taylor, Michael D., Read, Renee D., Kenney, Anna Marie
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6754407/
https://ncbi.nlm.nih.gov/pubmed/31541170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50088-1
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