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p53 Function is Compromised by Inhibitor 2 of Phosphatase 2A in Sonic Hedgehog Medulloblastoma

Medulloblastomas, the most common malignant pediatric brain tumors, have been genetically defined into four subclasses, namely WNT-activated, sonic hedgehog (SHH)-activated, Group 3 and Group 4. Approximately 30% of medulloblastomas have aberrant SHH signaling and thus are referred to as SHH-activat...

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書目詳細資料
發表在:Mol Cancer Res
Main Authors: Wei, Yun, Maximov, Victor, Morrissy, Sorana A., Taylor, Michael D., Pallas, David C., Kenney, Anna Marie
格式: Artigo
語言:Inglês
出版: 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6318027/
https://ncbi.nlm.nih.gov/pubmed/30224541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-0485
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