The WIP1 Oncogene Promotes Progression and Invasion of Aggressive Medulloblastoma Variants

Recent studies suggest that medulloblastoma, the most common malignant brain tumor of childhood, is comprised of four disease variants. The WIP1 oncogene is overexpressed in Group 3 and 4 tumors, which contain medulloblastomas with the most aggressive clinical behavior. Our data demonstrate increase...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Buss, Meghan C., Remke, Marc, Lee, Juhyun, Gandhi, Khanjan, Schniederjan, Matthew J., Kool, Marcel, Northcott, Paul A., Pfister, Stefan M., Taylor, Michael D., Castellino, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722800/
https://ncbi.nlm.nih.gov/pubmed/24632620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.37
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