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HDM2 promotes WIP1-mediated medulloblastoma growth

Medulloblastoma is the most common malignant childhood brain tumor. The protein phosphatase and oncogene WIP1 is over-expressed or amplified in a significant number of primary human medulloblastomas and cell lines. In the present study, we examine an important mechanism by which WIP1 promotes medull...

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Détails bibliographiques
Auteurs principaux: Buss, Meghan C., Read, Tracy-Ann, Schniederjan, Matthew J., Gandhi, Khanjan, Castellino, Robert C.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309853/
https://ncbi.nlm.nih.gov/pubmed/22379189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nos001
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