The WIP1 Oncogene Promotes Progression and Invasion of Aggressive Medulloblastoma Variants

Recent studies suggest that medulloblastoma, the most common malignant brain tumor of childhood, is comprised of four disease variants. The WIP1 oncogene is overexpressed in Group 3 and 4 tumors, which contain medulloblastomas with the most aggressive clinical behavior. Our data demonstrate increase...

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Foilsithe in:Oncogene
Main Authors: Buss, Meghan C., Remke, Marc, Lee, Juhyun, Gandhi, Khanjan, Schniederjan, Matthew J., Kool, Marcel, Northcott, Paul A., Pfister, Stefan M., Taylor, Michael D., Castellino, Robert C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722800/
https://ncbi.nlm.nih.gov/pubmed/24632620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.37
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