Medulloblastomas overexpress the p53-inactivating oncogene WIP1/PPM1D

Medulloblastoma is the most common malignant brain tumor of childhood. Despite numerous advances, clinical challenges range from recurrent and progressive disease to long-term toxicities in survivors. The lack of more effective, less toxic therapies results from our limited understanding of medullob...

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Autori principali: Castellino, Robert C., De Bortoli, Massimiliano, Lu, Xiongbin, Moon, Sung-Hwan, Nguyen, Thuy-Ai, Shepard, Mark A., Rao, Pulivarthi H., Donehower, Lawrence A., Kim, John Y. H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2007
Soggetti:
Lab. Investigation - Human/Animal Tissue
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174521/
https://ncbi.nlm.nih.gov/pubmed/17932621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-007-9470-8
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