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The Oncogenic Phosphatase WIP1 Negatively Regulates Nucleotide Excision Repair
Nucleotide excision repair (NER) is the only mechanism in humans to repair UV-induced DNA lesions such as pyrimidine (6–4) pyrimidone photoproducts and cyclobutane pyrimidine dimers (CPD). In response to UV damage, the ataxia telangiectasia mutated and Rad3-related (ATR) kinase phosphorylates and ac...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2893264/ https://ncbi.nlm.nih.gov/pubmed/20451471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.04.005 |
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