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Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background

Lymphoma is the most common hematological malignancy in developed countries. Outcome is strongly determined by molecular subtype, reflecting a need for new and improved treatment options. Dogs spontaneously develop lymphoma, and the predisposition of certain breeds indicates genetic risk factors. Us...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Elvers, Ingegerd, Turner-Maier, Jason, Swofford, Ross, Koltookian, Michele, Johnson, Jeremy, Stewart, Chip, Zhang, Cheng-Zhong, Schumacher, Steven E., Beroukhim, Rameen, Rosenberg, Mara, Thomas, Rachael, Mauceli, Evan, Getz, Gad, Palma, Federica Di, Modiano, Jaime F., Breen, Matthew, Lindblad-Toh, Kerstin, Alföldi, Jessica
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4617960/
https://ncbi.nlm.nih.gov/pubmed/26377837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.194449.115
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