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Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing
Retrotransposons constitute a major source of genetic variation, and somatic retrotransposon insertions have been reported in cancer. Here, we applied TranspoSeq, a computational framework that identifies retrotransposon insertions from sequencing data, to whole genomes from 200 tumor/normal pairs a...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4079962/ https://ncbi.nlm.nih.gov/pubmed/24823667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.163659.113 |
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