Somatic retrotransposition in human cancer revealed by whole-genome and exome sequencing

Retrotransposons constitute a major source of genetic variation, and somatic retrotransposon insertions have been reported in cancer. Here, we applied TranspoSeq, a computational framework that identifies retrotransposon insertions from sequencing data, to whole genomes from 200 tumor/normal pairs a...

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Detaylı Bibliyografya
Asıl Yazarlar: Helman, Elena, Lawrence, Michael S., Stewart, Chip, Sougnez, Carrie, Getz, Gad, Meyerson, Matthew
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2014
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4079962/
https://ncbi.nlm.nih.gov/pubmed/24823667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.163659.113
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