How do tumors make ends meet?

Por Lengauer, Christoph
Publicado em 2001

DNA methylation and genetic instability in colorectal cancer cells

Por Lengauer, Christoph, Kinzler, Kenneth W., Vogelstein, Bert
Publicado em 1997

Facile methods for generating human somatic cell gene knockouts using recombinant adeno-associated viruses

Por Kohli, Manu, Rago, Carlo, Lengauer, Christoph, Kinzler, Kenneth W., Vogelstein, Bert
Publicado em 2004

The landscape of kinase fusions in cancer

Por Stransky, Nicolas, Cerami, Ethan, Schalm, Stefanie, Kim, Joseph L., Lengauer, Christoph
Publicado em 2014

Targeting cancer with kinase inhibitors

Por Gross, Stefan, Rahal, Rami, Stransky, Nicolas, Lengauer, Christoph, Hoeflich, Klaus P.
Publicado no J Clin Invest (2015)

Evaluating Translocation Gene Fusions by SNP Array Data

Por Liu, Hong, Zilberstein, Asher, Pannier, Pascal, Fleche, Frederic, Arendt, Christopher, Lengauer, Christoph, Hahn, Chang S.
Publicado em 2011

Structural Comparisons of Class I Phosphoinositide 3-kinases

Por Amzel, L. Mario, Huang, Chuan-Hsiang, Mandelker, Diana, Lengauer, Christoph, Gabelli, Sandra B., Vogelstein, Bert
Publicado em 2008

An Evolutionary Approach for Identifying Driver Mutations in Colorectal Cancer

Por Foo, Jasmine, Liu, Lin L, Leder, Kevin, Riester, Markus, Iwasa, Yoh, Lengauer, Christoph, Michor, Franziska
Publicado no PLoS Comput Biol (2015)

Carcinogen-specific induction of genetic instability

Por Bardelli, Alberto, Cahill, Daniel P., Lederer, Gabi, Speicher, Michael R., Kinzler, Kenneth W., Vogelstein, Bert, Lengauer, Christoph
Publicado em 2001

SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells

Por Kohli, Manu, Yu, Jian, Seaman, Craig, Bardelli, Alberto, Kinzler, Kenneth W., Vogelstein, Bert, Lengauer, Christoph, Zhang, Lin
Publicado em 2004

Mechanisms underlying losses of heterozygosity in human colorectal cancers

Por Thiagalingam, Sam, Laken, Steve, Willson, James K. V., Markowitz, Sanford D., Kinzler, Kenneth W., Vogelstein, Bert, Lengauer, Christoph
Publicado em 2001

Digital karyotyping

Por Wang, Tian-Li, Maierhofer, Christine, Speicher, Michael R., Lengauer, Christoph, Vogelstein, Bert, Kinzler, Kenneth W., Velculescu, Victor E.
Publicado em 2002

The role of chromosomal instability in tumor initiation

Por Nowak, Martin A., Komarova, Natalia L., Sengupta, Anirvan, Jallepalli, Prasad V., Shih, Ie-Ming, Vogelstein, Bert, Lengauer, Christoph
Publicado em 2002

Targeting kinases with precision

Por Gardino, Alexandra K., Evans, Erica K., Kim, Joseph L., Brooijmans, Natasja, Hodous, Brian L., Wolf, Beni, Lengauer, Christoph
Publicado no Mol Cell Oncol (2018)

PTEN-deficient cancers depend on PIK3CB

Por Wee, Susan, Wiederschain, Dmitri, Maira, Sauveur-Michel, Loo, Alice, Miller, Christine, deBeaumont, Rosalie, Stegmeier, Frank, Yao, Yung-Mae, Lengauer, Christoph
Publicado em 2008

Disruption of p53 in human cancer cells alters the responses to therapeutic agents

Por Bunz, Fred, Hwang, Paul M., Torrance, Chris, Waldman, Todd, Zhang, Yonggang, Dillehay, Larry, Williams, Jerry, Lengauer, Christoph, Kinzler, Kenneth W., Vogelstein, Bert
Publicado em 1999

PI3Kα Inhibitors That Inhibit Metastasis

Por Schmidt-Kittler, Oleg, Zhu, Jiuxiang, Yang, Jian, Liu, Guosheng, Hendricks, William, Lengauer, Christoph, Gabelli, Sandra B., Kinzler, Kenneth W., Vogelstein, Bert, Huso, David L., Zhou, Shibin
Publicado em 2010

Crystal structure of human CDK4 in complex with a D-type cyclin

Por Day, Philip J., Cleasby, Anne, Tickle, Ian J., O'Reilly, Marc, Coyle, Joe E., Holding, Finn P., McMenamin, Rachel L., Yon, Jeff, Chopra, Rajiv, Lengauer, Christoph, Jhoti, Harren
Publicado em 2009

Inhibitory effects of midostaurin and avapritinib on myeloid progenitors derived from patients with KIT D816V positive advanced systemic mastocytosis

Por Lübke, Johannes, Naumann, Nicole, Kluger, Sebastian, Schwaab, Juliana, Metzgeroth, Georgia, Evans, Erica, Gardino, Alexandra K., Lengauer, Christoph, Hofmann, Wolf-Karsten, Fabarius, Alice, Cross, Nicholas C. P., Reiter, Andreas, Jawhar, Mohamad
Publicado no Leukemia (2019)

Contribution of Polycomb Homologues Bmi-1 and Mel-18 to Medulloblastoma Pathogenesis

Por Wiederschain, Dmitri, Chen, Lin, Johnson, Brett, Bettano, Kimberly, Jackson, Dowdy, Taraszka, John, Wang, Y. Karen, Jones, Michael D., Morrissey, Michael, Deeds, James, Mosher, Rebecca, Fordjour, Paul, Lengauer, Christoph, Benson, John D.
Publicado em 2007