Carcinogen-specific induction of genetic instability

It has been proposed recently that the type of genetic instability in cancer cells reflects the selection pressures exerted by specific carcinogens. We have tested this hypothesis by treating immortal, genetically stable human cells with representative carcinogens. We found that cells resistant to t...

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Bibliografiske detaljer
Main Authors: Bardelli, Alberto, Cahill, Daniel P., Lederer, Gabi, Speicher, Michael R., Kinzler, Kenneth W., Vogelstein, Bert, Lengauer, Christoph
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC33288/
https://ncbi.nlm.nih.gov/pubmed/11296254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.081082898
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