Carcinogen-specific induction of genetic instability

It has been proposed recently that the type of genetic instability in cancer cells reflects the selection pressures exerted by specific carcinogens. We have tested this hypothesis by treating immortal, genetically stable human cells with representative carcinogens. We found that cells resistant to t...

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Bibliographische Detailangaben
Hauptverfasser: Bardelli, Alberto, Cahill, Daniel P., Lederer, Gabi, Speicher, Michael R., Kinzler, Kenneth W., Vogelstein, Bert, Lengauer, Christoph
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 2001
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC33288/
https://ncbi.nlm.nih.gov/pubmed/11296254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.081082898
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