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Carcinogen-specific induction of genetic instability

It has been proposed recently that the type of genetic instability in cancer cells reflects the selection pressures exerted by specific carcinogens. We have tested this hypothesis by treating immortal, genetically stable human cells with representative carcinogens. We found that cells resistant to t...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Bardelli, Alberto, Cahill, Daniel P., Lederer, Gabi, Speicher, Michael R., Kinzler, Kenneth W., Vogelstein, Bert, Lengauer, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC33288/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11296254/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.081082898
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